4-Chloro-3-(2-chloroethyl)-2-methyl-6-(trifluoromethoxy)quinoline CAS 866133-05-3
| CAS No. | 866133-05-3 |
| Molecular Formula | C13H10Cl2F3NO |
| Molecular Weight | 324.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-3-(2-chloroethyl)-2-methyl-6-(trifluoromethoxy)quinoline (CAS 866133-05-3), molecular formula C13H10Cl2F3NO and molecular weight 324.13 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H10Cl2F3NO, 4-Chloro-3-(2-chloroethyl)-2-methyl-6-(trifluoromethoxy)quinoline contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 324.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-3-(2-chloroethyl)-2-methyl-6-(trifluoromethoxy)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10Cl2F3NO |
| Molecular Weight | 324.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Dimethyl 6-bromoquinoline-2,4-dicarboxylate (CAS 438590-10-4)
- 3-Bromo-N-(4-methoxyphenyl)-5-nitropyridin-4-amine (CAS 91394-81-9)
- 3-(Piperidin-3-yl)-3,4-dihydro-1H-benzo[c][1,2,6]thiadiazine 2,2-dioxide (CAS 1420816-74-5)
- 36361-79-2 5-benzyl-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one NS-03050 (CAS 36361-79-2)
- 1-((Tetrahydrofuran-2-yl)methyl)-1h-1,2,4-triazole-3-carbonitrile (CAS 1247499-68-8)
- 2-(1,3-Benzoxazol-2-yl)cyclopropanecarboxylic acid (CAS 1142214-36-5)
- 3-(Benzylcarbamoyl)phenylboronic Acid (CAS 625470-96-4)
- Siloxanes and Silicones, di-Me, 3-hydroxypropyl group-terminated (CAS 104780-66-7)
- Bis(1-propylguanidine), sulfuric acid (CAS 23483-93-4)
- 4-Amino-2-chloro-6-methylpyrimidine-5-carboxylic acid (CAS 1531671-00-7)
- Sodium Fluoride (CAS 7681-49-4)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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