3-((2-Bromobenzyl)amino)-1,1,1-trifluoropropan-2-ol CAS 866135-77-5
| CAS No. | 866135-77-5 |
| Molecular Formula | C10H11BrF3NO |
| Molecular Weight | 298.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((2-Bromobenzyl)amino)-1,1,1-trifluoropropan-2-ol (CAS 866135-77-5), molecular formula C10H11BrF3NO and molecular weight 298.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((2-Bromobenzyl)amino)-1,1,1-trifluoropropan-2-ol (C10H11BrF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((2-Bromobenzyl)amino)-1,1,1-trifluoropropan-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11BrF3NO |
| Molecular Weight | 298.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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- 2-Bromo-5-iodothiophene (CAS 29504-81-2)
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- 3-(2,4,6-Trifluorophenyl)-propionaldehyde (CAS 377084-11-2)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
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