2-((4-Chlorobenzyl)thio)-N'-(4-methylbenzoyl)benzohydrazide CAS 866136-27-8
| CAS No. | 866136-27-8 |
| Molecular Formula | C22H19ClN2O2S |
| Molecular Weight | 410.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((4-Chlorobenzyl)thio)-N'-(4-methylbenzoyl)benzohydrazide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((4-Chlorobenzyl)thio)-N'-(4-methylbenzoyl)benzohydrazide (CAS 866136-27-8), molecular formula C22H19ClN2O2S and molecular weight 410.92 g/mol, is a CATO reference standard with documented purity and traceability.
2-((4-Chlorobenzyl)thio)-N'-(4-methylbenzoyl)benzohydrazide (C22H19ClN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((4-Chlorobenzyl)thio)-N'-(4-methylbenzoyl)benzohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H19ClN2O2S |
| Molecular Weight | 410.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 7-(4-Chlorobenzyl)-3-(4-methoxybenzyl)-8-methyl-2,3,4,9-tetrahydro-6H-pyrimido[1,2-a][1,3,5]triazin-6-one (CAS 1374509-74-6)
- (5-((4-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl acetate (CAS 318469-50-0)
- 3,3-Bis(4-chlorobenzyl)-1-phenylpent-4-en-1-ol (CAS 1384881-74-6)
- 2-((4-Chlorobenzyl)thio)-5-(thieno[2,3-b]quinolin-2-yl)-1,3,4-oxadiazole (CAS 439112-42-2)
- 4-((4-Chlorobenzyl)thio)-2-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 5785-97-7)
- N-(2-chlorobenzyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide (CAS 1105235-17-3)
- 2-((6-((2-Chlorobenzyl)amino)pyrimidin-4-yl)thio)-N-(3-cyanophenyl)acetamide (CAS 1251573-02-0)
- 2-((4-Chlorobenzyl)thio)-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 387831-24-5)
Recommended Standards
- 10-(4-Chlorophenyl)-7-[(E)-2-phenylethenyl]-4-thia-6,10-diazatricyclo[6.3.0.0^{2,6}]undecane-9,11-dione (CAS 321522-01-4)
- 2-(Difluoromethyl)-3,5-diiodo-4-methoxypyridine (CAS 1804717-13-2)
- Sotagliflozin Impurity 7 (CAS CATO-C4X-30047)
- 4-(Difluoromethyl)-2,5-diiodo-3-methoxypyridine (CAS 1805010-71-2)
- 5-Nitrooxazole (CAS 125533-83-7)
- 4-Aminophenyl β-D-Mannopyranoside HCl (CAS 210049-18-6)
- 4-Bromo-5-(hydroxymethyl)-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 81122-69-2)
- Oclacitinib impurity 7 (CAS CATO-C4X-30187)
- Methyl (2R,4S)-4-Hydroxy-1-[(R)-1-phenylethyl]piperidine-2-carboxylate (CAS 177944-17-1)
- 3-Iodo-5-(methylthio)phenol (CAS 1243396-22-6)
- Carbazochrome Impurity 7 (CAS CATO-C4X-22917)
- 2-(3-Amino-4-bromo-1h-pyrazol-1-yl)propanamide (CAS 1249712-92-2)
- Amorolfine lmpurity 66 (CAS CATO-C4X-154266)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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