Ethyl 4-(methylthio)-2-thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydrothiazole-5-carboxylate CAS 866136-41-6
| CAS No. | 866136-41-6 |
| Molecular Formula | C14H12F3NO2S3 |
| Molecular Weight | 379.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-(methylthio)-2-thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydrothiazole-5-carboxylate.
Ethyl 4-(methylthio)-2-thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydrothiazole-5-carboxylate (CAS 866136-41-6) is a high-purity analytical reference standard with the molecular formula C14H12F3NO2S3 and a molecular weight of 379.44 g/mol.
Structurally, Ethyl 4-(methylthio)-2-thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydrothiazole-5-carboxylate (C14H12F3NO2S3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 379.44 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-(methylthio)-2-thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydrothiazole-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12F3NO2S3 |
| Molecular Weight | 379.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 3 |
Related Ethyl Standards
- 5-Methyl-2-(methylthio)-6-oxo-3,6-dihydropyrimidine-4-carboxylic acid (CAS 6635-65-0)
- 2-(4-(Methylthio)benzylidene)-6-phenyl-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 606956-72-3)
- 2-(Methylthio)-N-(4-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)phenyl)nicotinamide (CAS 756863-04-4)
- 3-(4-(Methylthio)phenyl)-5-(((1-phenyl-1H-imidazol-2-yl)thio)methyl)-1,2,4-oxadiazole (CAS 1115958-76-3)
- 5,5'-Bis(methylthio)-4,4'-diphenyl-4H,4'H-3,3'-bi(1,2,4-triazole) (CAS 637325-36-1)
- 2-(Methylthio)-N-(4-(naphthalen-2-yl)thiazol-2-yl)nicotinamide (CAS 786717-94-0)
- 2-(Methylthio)-N-(4-(5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl)nicotinamide (CAS 568558-04-3)
- 2-(Methylthio)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one (CAS 1300610-67-6)
Recommended Standards
- BAY 60-6583 (CAS 910487-58-0)
- ML150 (CAS 695209-67-7)
- 8-Amino-2-(ethylamino)-5-oxo-6-(p-tolyl)-4,6-dihydro-5H-pyrano[2,3-d]thiazolo[4,5-b]pyridine-7-carbonitrile (CAS 674800-51-2)
- Ilaprazole impurity 208 (CAS CATO-C4X-1130208)
- α-Methyl-5-pyrimidinemethanol-d3 (CAS 1346602-35-4)
- 2-Hydroxy-4-propoxy-benzaldehyde (CAS 63667-47-0)
- 4-Isopropoxy-3,5-dimethylbenzamide (CAS 1429901-44-9)
- 2-Butylthiazole-4-carboxylic acid (CAS 62657-88-9)
- 2-Chloro-N-[1-(1-methyl-1H-benzimidazol-2-yl)-ethyl]acetamide 2068AF 887573-34-4 C12H14ClN3O (CAS 887573-34-4)
- 4-Isopropyl-2-(methoxymethyl)pyrimidine-5-carboxylic acid (CAS 1249306-95-3)
- Irganox® 3125 (CAS 34137-09-2)
- 5-Fluoro-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 1506013-17-7)
- 4-(Azetidin-1-ylmethyl)-2-bromopyridine (CAS 1780773-95-6)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com