6-Benzoyl-2-(6-methoxypyridin-3-yl)-5-(trifluoromethyl)pyridazin-3(2H)-one CAS 866136-50-7
| CAS No. | 866136-50-7 |
| Molecular Formula | C18H12F3N3O3 |
| Molecular Weight | 375.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 6-Benzoyl-2-(6-methoxypyridin-3-yl)-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 866136-50-7), a certified reference material (molecular formula C18H12F3N3O3, MW 375.30 g/mol) for analytical method development and quality control.
The molecular framework of 6-Benzoyl-2-(6-methoxypyridin-3-yl)-5-(trifluoromethyl)pyridazin-3(2H)-one (C18H12F3N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6-Benzoyl-2-(6-methoxypyridin-3-yl)-5-(trifluoromethyl)pyridazin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12F3N3O3 |
| Molecular Weight | 375.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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