| CAS No. | 866136-68-7 |
| Molecular Formula | C19H21N5 |
| Molecular Weight | 319.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
4,8-Dimethyl-2-[4-(pyrimidin-2-yl)piperazin-1-yl]quinoline (CAS 866136-68-7) is a high-purity analytical reference standard with the molecular formula C19H21N5 and a molecular weight of 319.40 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 4,8-Dimethyl-2-[4-(pyrimidin-2-yl)piperazin-1-yl]quinoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C19H21N5 |
| Molecular Weight | 319.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |