4,8-Dimethyl-2-[4-(pyrimidin-2-yl)piperazin-1-yl]quinoline CAS 866136-68-7

Purity 97%+In StockPharmaceutical Standards
CAS No.866136-68-7
Molecular FormulaC19H21N5
Molecular Weight319.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,8-Dimethyl-2-[4-(pyrimidin-2-yl)piperazin-1-yl]quinoline CAS 866136-68-7 chemical structure

Description

4,8-Dimethyl-2-[4-(pyrimidin-2-yl)piperazin-1-yl]quinoline (CAS 866136-68-7) is a high-purity analytical reference standard with the molecular formula C19H21N5 and a molecular weight of 319.40 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 4,8-Dimethyl-2-[4-(pyrimidin-2-yl)piperazin-1-yl]quinoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC19H21N5
Molecular Weight319.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms5

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