N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-(p-tolylthio)acetamide CAS 866136-82-5

Purity 97%+In StockPharmaceutical Standards
CAS No.866136-82-5
Molecular FormulaC20H24FN3OS
Molecular Weight373.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-(p-tolylthio)acetamide CAS 866136-82-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 373.49 g/mol gives N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-(p-tolylthio)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-(p-tolylthio)acetamide (CAS 866136-82-5) is a high-purity analytical reference standard with the molecular formula C20H24FN3OS and a molecular weight of 373.49 g/mol.

Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-(p-tolylthio)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)-2-(p-tolylthio)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H24FN3OS
Molecular Weight373.49 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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