N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4-(3-(trifluoromethyl)phenyl)piperazine-1-carboxamide CAS 866137-34-0
| CAS No. | 866137-34-0 |
| Molecular Formula | C20H19F3N4O3 |
| Molecular Weight | 420.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4-(3-(trifluoromethyl)phenyl)piperazine-1-carboxamide (CAS 866137-34-0) is a high-purity analytical reference standard with the molecular formula C20H19F3N4O3 and a molecular weight of 420.39 g/mol.
The molecular framework of N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4-(3-(trifluoromethyl)phenyl)piperazine-1-carboxamide (C20H19F3N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4-(3-(trifluoromethyl)phenyl)piperazine-1-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H19F3N4O3 |
| Molecular Weight | 420.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
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