4-Chloro-3-[(naphthalen-1-yl)methylidene]-2,3-dihydro-1H-indol-2-one CAS 866137-60-2
| CAS No. | 866137-60-2 |
| Molecular Formula | C19H12ClNO |
| Molecular Weight | 305.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-3-[(naphthalen-1-yl)methylidene]-2,3-dihydro-1H-indol-2-one (CAS 866137-60-2), molecular formula C19H12ClNO and molecular weight 305.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-3-[(naphthalen-1-yl)methylidene]-2,3-dihydro-1H-indol-2-one (C19H12ClNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-3-[(naphthalen-1-yl)methylidene]-2,3-dihydro-1H-indol-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H12ClNO |
| Molecular Weight | 305.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 7-Nitrodibenzo[b,d]furan-2-sulfonamide (CAS 632301-17-8)
- 4-Bromo-5-(bromomethyl)-1-methyl-2-phenyl-1H-pyrazol-3(2H)-one (CAS 5767-66-8)
- N-(4-Amino-2-methoxyphenyl)-3-methylbutanamide (CAS 760204-87-3)
- N,N'-((1,4-diazepane-1,4-disulfonyl)bis(4,1-phenylene))diacetamide (CAS 547722-10-1)
- 4-Isopropyl-6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 2446483-88-9)
- (Chloromethyl)ethylbenzene (CAS 26968-58-1)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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