3-Bromo-8-chloro-2-(4-methoxyphenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 866137-67-9
| CAS No. | 866137-67-9 |
| Molecular Formula | C15H9BrClF3N2O |
| Molecular Weight | 405.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 3-Bromo-8-chloro-2-(4-methoxyphenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 866137-67-9), a certified reference material (molecular formula C15H9BrClF3N2O, MW 405.60 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-8-chloro-2-(4-methoxyphenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (C15H9BrClF3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9BrClF3N2O |
| Molecular Weight | 405.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-Bromo-5-chloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2,6-dimethoxybenzamide (CAS 82935-27-1)
- 4-Bromo-1,1,7,7-tetraethyl-3,3,5,5-tetramethyl-1,2,3,5,6,7-hexahydro-s-indacene (CAS 1142818-90-3)
- (3-Bromo-2,2-dimethylpropoxy)(tert-butyl)diphenylsilane (CAS 1310949-59-7)
- 1-Acetyl-5-bromo-4-chloro-1H-indol-3-yl phosphorodichloridate (CAS 132900-88-0)
- (4-Bromo-phenyl)-dImethyl-[2-(tetrahydro-pyran-2-yloxymethyl)-phenyl]-sIlane (CAS 953412-90-3)
- 2-bromo-1-(5-(tert-butyl)-[1,1'-biphenyl]-2-yl)-1H-benzo[d]imidazole (CAS CATO-CIM-105076)
- 2-Bromo-1-(5-(tert-butyl)-[1,1'-biphenyl]-2-yl)-1H-benzo[d]imidazole (CAS CATO-CIM-105080)
- 4-Bromo-N-(4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl)benzenesulfonamide (CAS 866156-51-6)
Recommended Standards
- 2,4,6-Trichlorophenyl 2-(trifluoromethyl)-benzenesulfonate (CAS 1171919-40-6)
- Dequalinium impurity 22 (CAS CATO-C4X-193622)
- 2,4,6-Trichlorophenyl 3-(trifluoromethyl)benzenesulfonate (CAS 1171919-24-6)
- Hydrolyzed Fumonisin B2 (CAS 147985-10-2)
- Tert-butyl (2-cyano-4-nitrophenyl)carbamate (CAS 1425945-81-8)
- (S)-3-(1-Amino-2,2,2-trifluoroethyl)aniline (CAS 1213520-51-4)
- N-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)cyclopentanamine (CAS 2096337-39-0)
- Methyl (2S,4S)-4-[2-(methoxycarbonyl)phenoxy]-2-pyrrolidinecarboxylate hydrochloride (CAS 1354486-85-3)
- n-((2,3-Dihydrobenzofuran-5-yl)methyl)propan-2-amine (CAS 1157544-05-2)
- (S)-2-(2-fluoro-6-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213378-49-4)
- 2-(2-Chloro-4-fluoro-5-methylphenyl)acetic acid (CAS 1000522-29-1)
- 3-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]propanoic acid (CAS 947013-67-4)
- Benzyl mandelate (CAS 890-98-2)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com