8-Chloro-2-(3,4-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 866137-80-6
| CAS No. | 866137-80-6 |
| Molecular Formula | C14H6Cl3F3N2 |
| Molecular Weight | 365.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Chloro-2-(3,4-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 866137-80-6), molecular formula C14H6Cl3F3N2 and molecular weight 365.57 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-Chloro-2-(3,4-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (C14H6Cl3F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 365.57 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Chloro-2-(3,4-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H6Cl3F3N2 |
| Molecular Weight | 365.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 8-Chloro-3-(2,6-dichlorophenyl)-6-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 1708126-02-6)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(2,4-dichlorophenyl)acetonitrile (CAS 213994-21-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(2,6-dichlorophenyl)acetonitrile (CAS 338407-06-0)
- 2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)propanoic acid (CAS 2387600-74-8)
- Ethyl 7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 2365242-44-8)
- 2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)-2-methylpropan-1-ol (CAS 2387600-30-6)
- 2-(7-Chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)butan-1-ol (CAS 2387601-52-5)
- 6-Chloro-2-iodo-3-(2-(thiophen-3-yl)ethoxy)pyridine (CAS 1282528-85-1)
Recommended Standards
- 5-(Benzyloxy)-1-bromo-3-chloro-2-(trifluoromethyl)benzene (CAS 2883770-70-3)
- (1R,5S,8s)-8-((tert-Butyldiphenylsilyl)oxy)-3-azabicyclo[3.2.1]octane (CAS 2763160-39-8)
- (3R,4R,5S)-4-(4-hydroxyphenyl)-5-((triisopropylsilyl)oxy)piperidin-3-ol (CAS 873945-31-4)
- Ethyl hydroxymethyl oleyl oxazoline (CAS 68140-98-7)
- (S)-Fmoc-2-Amino-5-(2,6-dichlorophenyl)pentanoic acid (CAS 2349562-40-7)
- 3,5-dibromo-6-cyclopropylpyridin-2-amine (CAS 1808846-52-7)
- 4-Ethyl-3-(furan-2-yl)-5-((naphthalen-1-ylmethyl)thio)-4H-1,2,4-triazole (CAS 618413-75-5)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridin-2-amine (CAS 2810048-41-8)
- 4-Hydroxymethyl-3-ethylphenylboronic acid pinacol ester (CAS 2121511-40-6)
- 2-Hydroxy-6-(2-naphthalen-1-yl-vinyl)-benzoic acid methyl ester (CAS 365542-22-9)
- Diethyl 6-benzyl-2,3-dihydro-6H-[1,4]dioxino[2,3-c]pyrrole-5,7-dicarboxylate (CAS 557795-97-8)
- Acetic anhydride-<SUP>13</SUP>C<SUB>4</SUB> (CAS 114510-14-4)
- 149457-83-0 Hypocrellin C (CAS 149457-83-0)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com