5-(4-Iodobenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one CAS 866138-25-2
| CAS No. | 866138-25-2 |
| Molecular Formula | C15H13IN2O3S |
| Molecular Weight | 428.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution, 5-(4-Iodobenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 428.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 5-(4-Iodobenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one (CAS 866138-25-2), a certified reference material (molecular formula C15H13IN2O3S, MW 428.24 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Iodobenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13IN2O3S |
| Molecular Weight | 428.24 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Iodobenzenesulfonyl Standards
- 4-(4-Iodobenzenesulfonyl)-1-oxa-4-azaspiro[4.5]decane (CAS 861209-87-2)
- 1-(4-Iodobenzenesulfonyl)piperidin-4-amine (CAS 1154258-05-5)
- 5-(4-Iodobenzenesulfonyl)-8-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861207-33-2)
- 1-(4-Iodobenzenesulfonyl)-3,4-bis(4-methoxyphenyl)-1H-pyrazole (CAS 956921-19-0)
- 4-Iodobenzenesulfonyl fluoride (CAS 4241-66-1)
Recommended Standards
- 3-Iodo-5-methoxy-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 945256-30-4)
- 1,4-Bis(bromomethyl)-2-methoxy-5-(2-ethylhexyloxy)benzene 2,5-Bis(bromomethyl)-1-methoxy-4-(2-ethylhexyloxy)benzene 2-Methoxy-5-(2-ethylhexyloxy)-1,4-bis(bromomethyl)benzene 209625-37-6 (CAS 209625-37-6)
- 1-(Benzylsulfonyl)-2-iodo-5-methoxy-1H-pyrrolo[3,2-b]pyridine (CAS 1352397-59-1)
- 2-Bromo-4-formyl-6-methoxyphenyl 4-acetamidobenzenesulfonate (CAS 1432436-62-8)
- 1-(Isoxazol-5-yl)ethan-1-amine (CAS 933721-75-6)
- N-((5-(Propylthio)-1,3,4-oxadiazol-2-yl)methyl)benzamide (CAS 941875-37-2)
- 7-Nitroso-1,7-dihydro-6H-purin-6-one (CAS CATO-C3D-26214)
- (2S,5R)-tert-Butyl 2-carbamoyl-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-1-carboxylate (CAS 934240-45-6)
- Tert-butyl 4-fluoro-2-methylpyrrolidine-1-carboxylate (CAS 1934832-12-8)
- 6-Chloro-N-(3-(trifluoromethyl)phenyl)nicotinamide (CAS 384847-78-3)
- 1-(3,4-Dichlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 957310-33-7)
- 3-Amino-6-chloro-2-iodopyridine (CAS 400777-06-2)
- tert-Butyl 8-bromo-5-fluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 1445891-41-7)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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