8-[3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl]-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one CAS 866142-43-0
| CAS No. | 866142-43-0 |
| Molecular Formula | C22H17NO6 |
| Molecular Weight | 391.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 391.37 g/mol gives 8-[3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl]-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-[3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl]-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one (CAS 866142-43-0), a certified reference material (molecular formula C22H17NO6, MW 391.37 g/mol) for analytical method development and quality control.
The molecular framework of 8-[3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl]-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one (C22H17NO6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-[3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl]-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17NO6 |
| Molecular Weight | 391.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 8-[4-Methoxy-3-(prop-2-yn-1-yloxy)phenyl]-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one (CAS 900018-70-4)
- 2-((5-Methoxy-2-methyl-4-nitrophenyl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 438597-02-5)
- 1-({[1-(2-methoxy-5-methylphenyl)-1H-tetrazol-5-yl]thio}acetyl)piperidine-4-carboxylic acid (CAS 731801-16-4)
- 4-Butyl-2-((4'-methoxy-1H,5'H-[2,2'-bipyrrol]-5'-ylidene)methyl)-1,4,5,6,7,8,9,10-octahydrocyclonona[b]pyrrole (CAS 352304-41-7)
- 1-(2-Methoxy-6-((4-methoxybenzyl)oxy)phenyl)-3,3-bis(methylthio)prop-2-en-1-one (CAS 1234015-62-3)
- 2-Methoxy-5-methyl-N-(2-(2-phenylmorpholino)ethyl)benzenesulfonamide (CAS 954048-46-5)
- 6-({7-methoxy-12,12-dimethyl-2-thia-4,6,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,9-pentaen-14-yl}amino)hexanoic acid (CAS 443312-67-2)
- 4-Methoxy-N-(2-oxo-2-(2-phenylmorpholino)ethyl)benzenesulfonamide (CAS 954038-85-8)
Recommended Standards
- 6,8-Dibromo-4-chloro-2-(trifluoromethyl)pyrido[3,4-d]pyrimidine (CAS 2119690-69-4)
- 1-(4-Fluorobenzyl)-N-(2-fluorophenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 946352-97-2)
- Glycoperine (CAS 55740-45-9)
- 5-(Benzyloxy)-1-(2,2-dimethoxyethyl)-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 1973401-99-8)
- 5-amino-2-fluoropyridine-4-carboxylic acid (CAS 171178-43-1)
- Fmoc-(2S,3S)-3-amino-2-hydroxy-5-methylhexanoic acid (CAS 361161-57-1)
- 1246815-98-4 N-Boc-N-ethylethylenediamine-d5 (CAS 1246815-98-4)
- 3-(Methylsulfonyl)-1-propanol (CAS 2058-49-3)
- 2-(4-Nitrophenyl)-1-(pyridin-3-yl)ethan-1-one (CAS 3769-99-1)
- Sodium Trifluoroacetate (CAS 2923-18-4)
- 2-((3-Chlorophenyl)amino)benzamide (CAS 13625-33-7)
- (2-Fluoro-5-((methyl(phenyl)amino)methyl)phenyl)boronic acid (CAS 1312922-65-8)
- 2-(3-(((1-(2,2-Difluoroethyl)-5-methyl-1H-pyrazol-4-yl)methyl)amino)-1H-pyrazol-1-yl)ethan-1-ol hydrochloride (CAS 1855943-74-6)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
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