4-Chloro-6-{[(2,6-dichlorophenyl)sulfanyl]methyl}-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine CAS 866143-67-1
| CAS No. | 866143-67-1 |
| Molecular Formula | C19H12Cl3F3N2S2 |
| Molecular Weight | 495.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6-{[(2,6-dichlorophenyl)sulfanyl]methyl}-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine.
4-Chloro-6-{[(2,6-dichlorophenyl)sulfanyl]methyl}-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine (CAS 866143-67-1), molecular formula C19H12Cl3F3N2S2 and molecular weight 495.80 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-6-{[(2,6-dichlorophenyl)sulfanyl]methyl}-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine (C19H12Cl3F3N2S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-6-{[(2,6-dichlorophenyl)sulfanyl]methyl}-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H12Cl3F3N2S2 |
| Molecular Weight | 495.80 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chloro Standards
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- 3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-N-(3,4-dichlorophenyl)-3-oxopropanamide (CAS 338392-28-2)
- 1-(2-(2-Chloro-6H-indolo[2,3-b]quinoxalin-6-yl)acetyl)-4-(4-hydroxybenzylidene)-3-methyl-1H-pyrazol-5(4H)-one (CAS 119457-13-5)
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- 3-[(3-Chloro-4-methoxyphenyl)methyl]-6,7-dimethoxy-2-{[(2-methylphenyl)methyl]sulfanyl}-3,4-dihydroquinazolin-4-imine (CAS 478249-80-8)
Recommended Standards
- N-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-isopropyl-1-phenanthrenyl]methyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]thiourea (CAS 1219925-57-1)
- 3,5,6,8-Tetrabromo-1,10-phenanthroline (CAS 66127-00-2)
- N-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-isopropyl-1-phenanthrenyl]methyl]-N'-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]thiourea (CAS 1219925-58-2)
- 90134-00-2 1-(3-Sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine Pyridinium, 4-(2-(6-(dibutylamino)-2-naphthalenyl)ethenyl)-1-(3-sulfopropyl)-, hydroxide, inner salt di-4-Anepps (CAS 90134-00-2)
- 1-Phenylhex-5-en-1-one (CAS 22524-25-0)
- Trans-methyl 4-butylcyclohexanecarboxylate (CAS 80361-60-0)
- 2-{pyrrolo[2,1-f][1,2,4]triazin-6-yl}ethan-1-amine (CAS 1547007-80-6)
- 5-Aminoadamantan-2-ol (CAS 22591-69-1)
- N,n-Diethyl-4-{[(prop-2-en-1-yl)amino]methyl}aniline dihydrochloride (CAS 1240568-98-2)
- 2-(pyrimidin-5-yl)acetamide (CAS 5267-02-7)
- Z-D-Lys(Boc)-OH (CAS 66845-42-9)
- [(4-chlorophenyl)(pyridin-4-yl)methyl](methyl)amine (CAS 1154311-80-4)
- 3-(4-Ethylphenyl)-1,1,1-trifluoropropan-2-ol (CAS 943904-02-7)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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