2-(6-Methoxypyridin-3-yl)-6-(oxirane-2-carbonyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one CAS 866143-78-4
| CAS No. | 866143-78-4 |
| Molecular Formula | C14H10F3N3O4 |
| Molecular Weight | 341.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(6-Methoxypyridin-3-yl)-6-(oxirane-2-carbonyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one.
2-(6-Methoxypyridin-3-yl)-6-(oxirane-2-carbonyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one (CAS 866143-78-4) is a high-purity analytical reference standard with the molecular formula C14H10F3N3O4 and a molecular weight of 341.24 g/mol.
2-(6-Methoxypyridin-3-yl)-6-(oxirane-2-carbonyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one (C14H10F3N3O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(6-Methoxypyridin-3-yl)-6-(oxirane-2-carbonyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10F3N3O4 |
| Molecular Weight | 341.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methoxypyridin Standards
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- Ethyl ((6-methoxypyridin-3-yl)carbamoyl)phenylalaninate (CAS 1396966-25-8)
- 3-[(6-Methoxypyridin-3-yl)amino]-2-phenyl-1H-inden-1-one (CAS 946385-83-7)
- N-(6-Methoxypyridin-3-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 864759-41-1)
- Methyl 7-(6-methoxypyridin-2-yl)-2-(methylsulfinyl)thieno[3,2-d]pyrimidine-6-carboxylate (CAS 1462949-96-7)
- 2-(6-Methoxypyridin-2-yl)-6-phenyl-1,3,6,2-dioxazaborocane (CAS 1133971-47-7)
- N-(6-methoxypyridin-3-yl)naphthalene-2-sulfonamide (CAS 680591-15-5)
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Recommended Standards
- 2-(4-Bromo-2-((cyclohexylamino)methyl)phenoxy)acetamide (CAS 852698-02-3)
- 2,4-Dioxo-1-(2-(3-(trifluoromethyl)phenoxy)ethoxy)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 339010-24-1)
- 1-Boc-4-(4-Bromophenyl)piperazine (CAS 352437-09-3)
- 3-(Tert-butyl)-1-(2,4-dichlorobenzyl)-1H-pyrazole-5-carbohydrazide (CAS 306937-07-5)
- Bicyclo[2.2.1]heptan-2-ol (CAS 1632-68-4)
- 1H-indazole-3,5-dicarboxylic acid (CAS 885520-06-9)
- Caesappanin C (CAS 1913319-59-1)
- 3,3-Bis(fluoromethyl)cyclobutan-1-amine (CAS 2169136-20-1)
- methyl 5-amino-1-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 1630907-29-7)
- (E)-N-(2-(4-Methoxyphenyl)-1-(tributylstannyl)vinyl)formamide (CAS 862263-31-8)
- 3-((2-Ethyl-2-hydroxybutyl)amino)thietane 1,1-dioxide (CAS 1878770-53-6)
- 6,7-Difluorobenzo[d]isoxazol-3(2h)-one (CAS 1223451-39-5)
- N-methyl-2-(pyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine (CAS 885951-06-4)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
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