2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-phenyl-N-(thiazol-2-yl)acetamide CAS 866144-86-7
| CAS No. | 866144-86-7 |
| Molecular Formula | C21H19ClF3N5OS |
| Molecular Weight | 481.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-phenyl-N-(thiazol-2-yl)acetamide (C21H19ClF3N5OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-phenyl-N-(thiazol-2-yl)acetamide (CAS 866144-86-7), molecular formula C21H19ClF3N5OS and molecular weight 481.92 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-phenyl-N-(thiazol-2-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19ClF3N5OS |
| Molecular Weight | 481.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-1-oxo-1,2-dihydroisoquinolin-4-yl)morpholine-4-carboxamide (CAS 400075-74-3)
- 1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[trans-4-[[5-(trifluoromethyl)pyridin-2-yl]oxy]cyclohexyl]urea (CAS 1394011-91-6)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-2-oxoethyl 3-(furan-2-carboxamido)-4-methylbenzoate (CAS 479060-67-8)
- 2-((4-Chloro-N-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)phenyl)sulfonamido)-N-methylacetamide (CAS 338967-67-2)
- 3-Chloro-2-(3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1H-pyrazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 477711-65-2)
- Ethyl 4-{4-[2-chloro-4-(4-chlorophenoxy)benzoyl]-1H-1,2,3-triazol-1-yl}benzoate (CAS 478248-76-9)
- 3-Chloro-2-((3,4-dibromo-3,4,4-trifluorobutyl)thio)-5-(trifluoromethyl)pyridine (CAS 478081-07-1)
- 2-Chloro-5-(5-((4-chlorobenzyl)thio)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)pyridine (CAS 680216-98-2)
Recommended Standards
- Cefdinir Impurity25 (CAS 1637542-33-6)
- N-[(2H-1,3-Benzodioxol-5-yl)methyl]-2-[4-(5-chloro-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)piperazin-1-yl]acetamide (CAS 924249-06-9)
- 2,4-Dibromo-6-[(1E)-[(5-iodopyridin-2-yl)imino]methyl]phenol (CAS 401832-64-2)
- Avanafil Impurity 105 (CAS CATO-C4X-1118105)
- 6-Bromobenzo[b]thiophene-2-carbohydrazide (CAS 1171927-47-1)
- 4-Methyl-2-(piperazin-1-yl)thiazole-5-carboxylic acid (CAS 1104278-96-7)
- 4-Bromo-3-chlorophenylacetonitrile (CAS 1259023-29-4)
- Tetrahydro-5-methyl-2-furanol (CAS 18545-25-0)
- 2-Hydroxycyclopent-2-en-1-one (CAS 10493-98-8)
- Valdecoxib Sulfonyl Chloride-13C2,15N (CAS 1391051-92-5)
- 6-Desamino 6-Chloro Etravirine (CAS 269055-76-7)
- 2-(2-([1,1'-Biphenyl]-4-yl)acetamido)thiophene-3-carboxamide (CAS 756849-36-2)
- 2-[(2-fluorophenyl)methyl]piperidine hydrochloride (CAS 1955492-78-0)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
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