1-{4-[3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl}-1,4-dihydropyridin-4-one CAS 866144-91-4
| CAS No. | 866144-91-4 |
| Molecular Formula | C25H20N4O3 |
| Molecular Weight | 424.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-{4-[3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl}-1,4-dihydropyridin-4-one (C25H20N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-{4-[3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl}-1,4-dihydropyridin-4-one (CAS 866144-91-4), a certified reference material (molecular formula C25H20N4O3, MW 424.45 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H20N4O3 |
| Molecular Weight | 424.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related dimethoxyphenyl Standards
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- (5Z)-5-{[3-(3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 882218-76-0)
- 1-{2-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-(3-methylphenoxy)ethan-1-one (CAS 1798499-85-0)
- (2E)-3-[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]-2-(4-fluorophenyl)prop-2-enenitrile (CAS 957025-98-8)
- 11-(3,4-Dimethoxyphenyl)-6-hydroxy-13-(trifluoromethyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5,10,12-pentaen-4-one (CAS 674805-72-2)
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- 3-(3,5-Dimethoxyphenyl)-5-(5-(((3-methylbenzyl)thio)methyl)furan-2-yl)-1,2,4-oxadiazole (CAS 1114908-82-5)
Recommended Standards
- 1-(4-Methoxybenzyl)-2-oxo-N-(3,4,5-trimethoxyphenyl)-1,2-dihydropyridine-3-carboxamide (CAS 400077-78-3)
- 10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414254-47-8)
- (S)-10-Cyclopropyl-1-(9H-fluoren-9-yl)-3,6-dioxo-2,9-dioxa-4,7-diazaundecan-11-oic acid (CAS 2414393-57-8)
- 2-Acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosyl Azide (CAS 80887-27-0)
- 4-(Hydroxymethyl)cubane-1-carbonitrile (CAS 2108376-05-0)
- N3,N3',N5,N5'-Tetrahydroxy-[1,1'-biphenyl]-3,3',5,5'-tetracarboxamide (CAS 2414312-65-3)
- 3-Amino-2-(2-chlorophenyl)propanoic acid hydrochloride (CAS 1858251-10-1)
- 2-Bromo-3-(piperidin-1-yl)prop-1-ene (CAS 37828-88-9)
- 5-Bromo-1-fluoro-2-(methoxymethoxy)-3-(trifluoromethyl)benzene (CAS 2413441-33-3)
- 1-[(2-Hydroxyethyl)thio]-2-propanol (CAS 6713-03-7)
- 2-(3-Nitrophenyl)propan-2-amine (CAS 1030137-68-8)
- 1-(4-Chlorophenyl)-2-iodoethan-1-ol (CAS 256380-97-9)
- 2-Bromo-3-chloro-5-iodothiophene (CAS 1499838-60-6)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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