(1-Methyl-5-((4-(pyrimidin-2-yl)piperazin-1-yl)methyl)-1H-pyrrol-3-yl)(phenyl)methanone CAS 866149-63-5
| CAS No. | 866149-63-5 |
| Molecular Formula | C21H23N5O |
| Molecular Weight | 361.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (1-Methyl-5-((4-(pyrimidin-2-yl)piperazin-1-yl)methyl)-1H-pyrrol-3-yl)(phenyl)methanone is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(1-Methyl-5-((4-(pyrimidin-2-yl)piperazin-1-yl)methyl)-1H-pyrrol-3-yl)(phenyl)methanone (CAS 866149-63-5), molecular formula C21H23N5O and molecular weight 361.44 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (1-Methyl-5-((4-(pyrimidin-2-yl)piperazin-1-yl)methyl)-1H-pyrrol-3-yl)(phenyl)methanone (C21H23N5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (1-Methyl-5-((4-(pyrimidin-2-yl)piperazin-1-yl)methyl)-1H-pyrrol-3-yl)(phenyl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23N5O |
| Molecular Weight | 361.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Methyl Standards
- Ethyl 5-((1-(pyrimidin-2-yl)piperidine-4-carboxamido)methyl)-4,5-dihydroisoxazole-3-carboxylate (CAS 306978-06-3)
- Ethyl 1'-(pyrimidin-2-yl)-3a,4,8,8a-tetrahydrospiro[[1,3]dioxepino[5,6-d][1,2]oxazole-6,4'-piperidine]-3-carboxylate (CAS 303152-98-9)
- 4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 2-(thiophen-2-yl)acetate (CAS 877637-56-4)
- 4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 2-fluorobenzoate (CAS 877636-12-9)
- (4-(Pyrimidin-2-yloxy)piperidin-1-yl)(1-(thiophen-2-yl)cyclopentyl)methanone (CAS 1421493-45-9)
- [[2-Oxo-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]-(phenyl)amino]acetic acid (CAS 1142211-53-7)
- (S)-3-(Pyrimidin-2-ylamino)-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 1289384-86-6)
- 4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 2-methylbenzoate (CAS 877635-25-1)
Recommended Standards
- 1,8-Bis[(4S)-4-ethyl-4,5-dihydro-2-oxazolyl]-9H-carbazole (CAS 1895031-52-3)
- (2E)-N-[3-(1H-Imidazol-1-yl)propyl]-3-(2-methoxyphenyl)-2-phenylprop-2-enamide (CAS 478064-18-5)
- 5-Fluoro AMB Metabolite 2 (CAS 1890250-14-2)
- 1-(4-(4-Fluorophenyl)-5-(2-morpholinoethyl)pyrimidin-2-yl)thiourea (CAS 866142-55-4)
- (S)-4-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride (CAS 2177263-58-8)
- 1-(3-Methyl-4-(oxetan-3-yl)phenyl)ethanamine (CAS 1823958-77-5)
- 6-(4-Methoxyphenyl)pyridazin-3-amine (CAS 4776-87-8)
- Methyl 5-amino-6-bromo-3-methylpyrazine-2-carboxylate (CAS 1823921-17-0)
- 2-Chloro-4-fluoronicotinic Acid (CAS 929022-76-4)
- 4-(4-Methoxyphenyl)butyric Acid (CAS 4521-28-2)
- Tert-butyl 1-fluoro-5-methoxy-3-azabicyclo[3.1.1]Heptane-3-carboxylate (CAS 2413900-24-8)
- N-(2H-1,3-benzodioxol-5-ylmethyl)-4-methylcyclohexan-1-amine (CAS 1038286-10-0)
- 1-Methoxy-3-(oxan-4-yl)propan-2-amine (CAS 1249772-50-6)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com