1-(Benzo[d][1,3]dioxol-5-ylmethyl)-4-((2-(prop-2-yn-1-yloxy)naphthalen-1-yl)methyl)piperazine CAS 866149-68-0
| CAS No. | 866149-68-0 |
| Molecular Formula | C26H26N2O3 |
| Molecular Weight | 414.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(Benzo[d][1,3]dioxol-5-ylmethyl)-4-((2-(prop-2-yn-1-yloxy)naphthalen-1-yl)methyl)piperazine (CAS 866149-68-0), molecular formula C26H26N2O3 and molecular weight 414.50 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Benzo[d][1,3]dioxol-5-ylmethyl)-4-((2-(prop-2-yn-1-yloxy)naphthalen-1-yl)methyl)piperazine (C26H26N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26N2O3 |
| Molecular Weight | 414.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Benzo Standards
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Recommended Standards
- JWH 198 (CAS 166599-76-4)
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- 1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-diol (CAS 85555-67-5)
- N-(4-(3-Methylimidazo[2,1-b]thiazol-6-yl)phenyl)cyclopropanecarboxamide (CAS 893985-81-4)
- 3-methanesulfonylpyridine (CAS 52693-61-5)
- 5,7-Dichloro-3-methylisoquinolin-1(2H)-one (CAS 1596809-16-3)
- 4,4-Difluorocyclohexanecarbonyl Chloride (CAS 376348-75-3)
- Myristamidopropyl Dimethylamine (CAS 45267-19-4)
- 2-(2-Benzamidoacetamido)ethyl benzoate (CAS 338419-48-0)
- Methyl (2-(1-hydroxy-1H-indol-3-yl)ethyl)carbamate (CAS 180910-53-6)
- 2-(5-Chloro-1H-indazol-3-yl)acetamide (CAS 887145-79-1)
- 2,6-Dichloropyridin-4-amine Hydrochloride (CAS 1049730-38-2)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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