5-[2-Chloro-4-(trifluoromethyl)phenoxy]-2-(2-fluorophenyl)-2,3-dihydro-1H-isoindole-1,3-dione CAS 866150-55-2
| CAS No. | 866150-55-2 |
| Molecular Formula | C21H10ClF4NO3 |
| Molecular Weight | 435.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-[2-Chloro-4-(trifluoromethyl)phenoxy]-2-(2-fluorophenyl)-2,3-dihydro-1H-isoindole-1,3-dione is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-[2-Chloro-4-(trifluoromethyl)phenoxy]-2-(2-fluorophenyl)-2,3-dihydro-1H-isoindole-1,3-dione (CAS 866150-55-2), a certified reference material (molecular formula C21H10ClF4NO3, MW 435.76 g/mol) for analytical method development and quality control.
Structurally, 5-[2-Chloro-4-(trifluoromethyl)phenoxy]-2-(2-fluorophenyl)-2,3-dihydro-1H-isoindole-1,3-dione (C21H10ClF4NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 435.76 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H10ClF4NO3 |
| Molecular Weight | 435.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 338791-68-7)
- 1'-[(2E)-3-[4-chloro-3-(trifluoromethyl)phenyl]-2-propen-1-yl]-spiro[imidazolidine-4,3'-[3H]indole]- (CAS 945736-64-1)
- 5-Chloro-1-[(3,4-dichlorophenyl)methyl]-N-(2,6-dimethylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 339008-88-7)
- 3-(5-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-1H-pyrazol-1-yl)-5-methyl-4H-1,2,4-triazol-4-amine (CAS 318959-14-7)
- 2-Chloro-7-iodo-5-(triisopropylsilyl)-5H-pyrrolo[2,3-b]pyrazine (CAS 1184852-48-9)
- 2-(3-(4-Chloro-2-(2,6-difluorobenzoyl)phenyl)prop-2-ynyl)isoindoline-1,3-dione (CAS 1415560-50-7)
- 4-Chloro-N-[5-oxo-2,4-bis(trifluoromethyl)-5,6-dihydro-1,6-naphthyridin-6-yl]benzamide (CAS 860785-18-8)
- Methyl 4-((4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)methyl)benzoate (CAS 338415-83-1)
Recommended Standards
- 6-(4-Chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-4-(methylsulfanyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 478042-95-4)
- N,N-Diethyl-3-methoxy-propionamide (CAS 5830-19-3)
- 6-(4-Chlorophenyl)-1-[(2,6-dichlorophenyl)methyl]-4-(methylsulfanyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 478042-89-6)
- N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-2-chloro-N-(3,5-dimethylphenyl)acetamide (CAS 727696-08-4)
- Methyl 2-amino-6-methoxypyrimidine-4-carboxylate (CAS 365413-28-1)
- 1-(4-Fluorobenzyl)-2-methyl-1H-indole-3-carbaldehyde (CAS 332922-15-3)
- 2-(4-Nitrophenyl)-N,6-diphenylpyrimidin-4-amine (CAS 352224-38-5)
- Diclazuril (CAS 101831-37-2)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-{3-[5-(trifluoromethyl)pyridin-2-yl]phenyl}benzene-1-sulfonamide (CAS 1092346-23-0)
- 2-[(3-Morpholin-4-ylpropyl)amino]-5-nitrobenzonitrile (CAS 451459-94-2)
- 4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-2-en-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile (CAS CATO-C3D-2418)
- Dichloro[N-(1,1-dimethylethyl)-1,1-dimethyl-1-[(1,2,3,3a,7a-η)-3-(1-pyrrolidinyl)-1H-inden-1-yl]silanaminato(2-)-κN]titanium (CAS 203067-69-0)
- (1-((4-Fluorophenyl)sulfonyl)piperidine-4-carbonyl)glycine (CAS 929969-80-2)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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