(2Z)-3-(4-tert-Butylphenyl)-2-cyano-N-(2-fluoro-5-methylphenyl)-3-hydroxyprop-2-enamide CAS 866151-41-9

Purity 97%+In StockPharmaceutical Standards
CAS No.866151-41-9
Molecular FormulaC21H21FN2O2
Molecular Weight352.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2Z)-3-(4-tert-Butylphenyl)-2-cyano-N-(2-fluoro-5-methylphenyl)-3-hydroxyprop-2-enamide CAS 866151-41-9 chemical structure

Description

The occurrence of (2Z)-3-(4-tert-Butylphenyl)-2-cyano-N-(2-fluoro-5-methylphenyl)-3-hydroxyprop-2-enamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2Z)-3-(4-tert-Butylphenyl)-2-cyano-N-(2-fluoro-5-methylphenyl)-3-hydroxyprop-2-enamide (CAS 866151-41-9) is a high-purity analytical reference standard with the molecular formula C21H21FN2O2 and a molecular weight of 352.40 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (2Z)-3-(4-tert-Butylphenyl)-2-cyano-N-(2-fluoro-5-methylphenyl)-3-hydroxyprop-2-enamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 352.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2Z)-3-(4-tert-Butylphenyl)-2-cyano-N-(2-fluoro-5-methylphenyl)-3-hydroxyprop-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC21H21FN2O2
Molecular Weight352.40 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms2

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