1-(4-Chlorophenyl)-2-(4,5-dichloro-1H-imidazol-1-yl)-1-(4-fluorophenyl)ethan-1-ol CAS 866151-53-3
| CAS No. | 866151-53-3 |
| Molecular Formula | C17H12Cl3FN2O |
| Molecular Weight | 385.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-(4-Chlorophenyl)-2-(4,5-dichloro-1H-imidazol-1-yl)-1-(4-fluorophenyl)ethan-1-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-(4-Chlorophenyl)-2-(4,5-dichloro-1H-imidazol-1-yl)-1-(4-fluorophenyl)ethan-1-ol (CAS 866151-53-3), molecular formula C17H12Cl3FN2O and molecular weight 385.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Chlorophenyl)-2-(4,5-dichloro-1H-imidazol-1-yl)-1-(4-fluorophenyl)ethan-1-ol (C17H12Cl3FN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H12Cl3FN2O |
| Molecular Weight | 385.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-(4-Chlorophenyl)-3-((4-iodophenyl)amino)propan-1-one (CAS 477320-54-0)
- 1-(2-Chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-99-3)
- 1-(3-Chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-96-0)
- 1-(4-Chlorophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-92-6)
- 2-((3-Chlorophenyl)sulfonyl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 339014-04-9)
- 2-(4-Chlorophenyl)-4-[4-(trifluoromethyl)phenyl]thiomorpholine-3,5-dione (CAS 252058-83-6)
- Ethyl 4-{[(4-chlorophenyl)methyl]amino}-6-nitroquinoline-3-carboxylate (CAS 478248-26-9)
- N-(4-chlorophenyl)-N-((3,4-dimethoxyphenyl)sulfonyl)glycine (CAS 713501-82-7)
Recommended Standards
- 3-Chloro-2-oxo-5,5'-bis(trifluoromethyl)-2H-[1,3'-bipyridine]-2'-carboxamide (CAS 1823182-37-1)
- (2S,3S,5S)-2-Hexyl-3,5-dihydroxyhexadecanoic Acid-d13 (CAS 1217806-00-2)
- 2-Chloro-N-(4-(trifluoromethoxy)phenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 154563-52-7)
- 5-Bromo-2-chloro-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227269-09-1)
- 3-(2-Fluorophenyl)-5-nitro-1H-indazole (CAS 1356087-61-0)
- 4-(Benzo[d]thiazol-2-ylthio)but-2-yn-1-ol (CAS 431067-90-2)
- Methyl 3-(1-methyl-1H-pyrazol-4-yl)propiolate (CAS 1342965-27-8)
- 2-Oxo-1-(thiazol-2-ylcarbamoylmethyl)-1,2-dihydro-pyridine-3-carboxylic acid (CAS 1171917-16-0)
- (S)-1-(2,5-Diethoxyphenyl)ethan-1-ol (CAS 1177200-51-9)
- 4-(1H-Indol-3-yl)pyrimidin-2-amine (CAS 289628-76-8)
- 5,5-Dimethyl-3-propylimidazolidine-2,4-dione (CAS 97304-48-8)
- 7-Chloro-4-(3,4-diethoxybenzyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1326937-73-8)
- 1-[4-(Benzyloxy)phenyl]-3-[(2,6-dichlorophenyl)methyl]-2-methyl-1,4-dihydropyridin-4-one (CAS 339017-25-3)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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