2,6-Dichloro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzamide CAS 866151-59-9

Purity 97%+In StockPharmaceutical Standards
CAS No.866151-59-9
Molecular FormulaC18H17Cl2NO2
Molecular Weight350.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-Dichloro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzamide CAS 866151-59-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 350.24 g/mol gives 2,6-Dichloro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,6-Dichloro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzamide (CAS 866151-59-9) is a high-purity analytical reference standard with the molecular formula C18H17Cl2NO2 and a molecular weight of 350.24 g/mol.

2,6-Dichloro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzamide (C18H17Cl2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,6-Dichloro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H17Cl2NO2
Molecular Weight350.24 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms1

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