(E)-1-morpholino-3-(3-((4-(trifluoromethyl)benzyl)oxy)phenyl)prop-2-en-1-one CAS 866151-69-1
| CAS No. | 866151-69-1 |
| Molecular Formula | C21H20F3NO3 |
| Molecular Weight | 391.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-1-morpholino-3-(3-((4-(trifluoromethyl)benzyl)oxy)phenyl)prop-2-en-1-one.
CATO supplies (E)-1-morpholino-3-(3-((4-(trifluoromethyl)benzyl)oxy)phenyl)prop-2-en-1-one (CAS 866151-69-1), a certified reference material (molecular formula C21H20F3NO3, MW 391.38 g/mol) for analytical method development and quality control.
Structurally, (E)-1-morpholino-3-(3-((4-(trifluoromethyl)benzyl)oxy)phenyl)prop-2-en-1-one (C21H20F3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 391.38 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H20F3NO3 |
| Molecular Weight | 391.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
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Recommended Standards
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,4,5-trifluorophenyl)methanone (CAS 898758-52-6)
- (E)-4-(2-fluorostyryl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (CAS 866133-27-9)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,4,5-trifluorophenyl)methanone (CAS 898762-43-1)
- (E)-4-(4-fluorostyryl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (CAS 866133-47-3)
- (4-[(2-fluorophenyl)methoxy]phenyl)methanol (CAS 690963-48-5)
- 2-((Benzyloxy)carbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1260637-46-4)
- Methyl 2-(2-((2-fluorophenoxy)methyl)morpholino)acetate (CAS 1706440-35-8)
- Huperzine A Impurity 1 (CAS CATO-C4X-31231)
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- 2-(P-tolyl)butan-2-ol (CAS 5398-04-9)
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