(2E)-N-(Prop-2-en-1-yl)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enamide CAS 866152-11-6

Purity 97%+In StockPharmaceutical Standards
CAS No.866152-11-6
Molecular FormulaC20H18F3NO2
Molecular Weight361.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-N-(Prop-2-en-1-yl)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enamide CAS 866152-11-6 chemical structure

Description

The occurrence of (2E)-N-(Prop-2-en-1-yl)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2E)-N-(Prop-2-en-1-yl)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enamide (CAS 866152-11-6) is a high-purity analytical reference standard with the molecular formula C20H18F3NO2 and a molecular weight of 361.36 g/mol.

(2E)-N-(Prop-2-en-1-yl)-3-(3-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)prop-2-enamide (C20H18F3NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H18F3NO2
Molecular Weight361.36 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms1

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