1-(3,4-Dichlorobenzyl)-5-nitrospiro[indoline-3,2'-[1,3]dioxolan]-2-one CAS 866152-45-6
| CAS No. | 866152-45-6 |
| Molecular Formula | C17H12Cl2N2O5 |
| Molecular Weight | 395.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3,4-Dichlorobenzyl)-5-nitrospiro[indoline-3,2'-[1,3]dioxolan]-2-one is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(3,4-Dichlorobenzyl)-5-nitrospiro[indoline-3,2'-[1,3]dioxolan]-2-one (CAS 866152-45-6), a certified reference material (molecular formula C17H12Cl2N2O5, MW 395.19 g/mol) for analytical method development and quality control.
Structurally, 1-(3,4-Dichlorobenzyl)-5-nitrospiro[indoline-3,2'-[1,3]dioxolan]-2-one (C17H12Cl2N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 395.19 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H12Cl2N2O5 |
| Molecular Weight | 395.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorobenzyl Standards
- 7-(3-((2,4-Dichlorobenzyl)oxy)phenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 478046-39-8)
- 1-(2,6-Dichlorobenzyl)-3-(2,6-dimethylmorpholine-4-carbonyl)pyridin-2(1H)-one (CAS 478048-20-3)
- 2-Benzyl-4-((2,6-dichlorobenzyl)oxy)quinazoline (CAS 400078-69-5)
- N-(1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methylpiperazine-1-carboxamide (CAS 338755-44-5)
- 1-(2,4-Dichlorobenzyl)-3-(4-ethyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 860649-41-8)
- 1-(2,4-Dichlorobenzyl)-3-(5-(ethylthio)-4-methyl-4H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 339016-74-9)
- 3-((2,6-Dichlorobenzyl)thio)-N-phenylthiophene-2-carboxamide (CAS 251097-42-4)
- Ethyl 4-(2,4-dichlorobenzyl)-3-methyl-4H-1,4-benzothiazine-2-carboxylate (CAS 339098-13-4)
Recommended Standards
- 1-(2H-1,3-Benzodioxol-5-yl)-3-[(4-iodophenyl)amino]propan-1-one (CAS 883794-43-2)
- 2-Iodo-1,3-dimethoxy-10-methylacridin-9(10H)-one (CAS 88901-71-7)
- 2-Bromo-N-(2-(2-fluorobenzoyl)-4-nitrophenyl)-N-methylacetamide (CAS 70931-08-7)
- Methyl 2-(8-bromo-1,3-difluorophenanthren-2-yl)-2-hydroxypropanoate (CAS 843614-83-5)
- (1-Allyl-1H-benzo[d]imidazol-2-yl)methanol (CAS 300706-95-0)
- 3-Methoxy-N-[4-(phenethyloxy)benzyl]-1-propanamine (CAS 1040680-93-0)
- 2-(3-Bromo-4-hydroxy-5-methoxyphenyl)acetic acid (CAS 206559-42-4)
- 2,5-dihydrothiophene-3-carboxylic acid (CAS 98508-62-4)
- 1-(4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-3-fluorophenyl)cyclobutanol (CAS 1467060-17-8)
- 2-{1-[(tert-butoxy)carbonyl]-4-hydroxypiperidin-4-yl}-2-methylpropanoic acid (CAS 1251032-53-7)
- 5-Nitro-6-(p-tolylthio)imidazo[2,1-b]thiazole (CAS 343376-28-3)
- 2-((1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)-5-(trifluoromethyl)pyridine (CAS 477711-82-3)
- 4-Methyl-8-quinoxalinesulfonyl Chloride (CAS 13982-84-8)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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