(2Z)-2-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2H,3H,5H,6H,7H-[1,3]thiazolo[3,2-a]pyrimidin-3-one CAS 866153-38-0
| CAS No. | 866153-38-0 |
| Molecular Formula | C14H14N2O3S |
| Molecular Weight | 290.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2Z)-2-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2H,3H,5H,6H,7H-[1,3]thiazolo[3,2-a]pyrimidin-3-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2Z)-2-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2H,3H,5H,6H,7H-[1,3]thiazolo[3,2-a]pyrimidin-3-one (CAS 866153-38-0), molecular formula C14H14N2O3S and molecular weight 290.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2Z)-2-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2H,3H,5H,6H,7H-[1,3]thiazolo[3,2-a]pyrimidin-3-one (C14H14N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2Z)-2-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2H,3H,5H,6H,7H-[1,3]thiazolo[3,2-a]pyrimidin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O3S |
| Molecular Weight | 290.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 1,9-dioxaspiro[5.5]undecan-4-ylmethanamine hydrochloride (CAS 2060000-35-1)
- (E)-2-(1-nitronaphthalen-2-yl)acetaldehyde O-methyl oxime (CAS 339100-56-0)
- 3-(1-{[(tert-butoxy)carbonyl]amino}ethyl)-1,2-oxazole-4-carboxylic acid (CAS 1334491-40-5)
- 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-5-ol hydrochloride (CAS 1628638-77-6)
- (R)-2-nitro-6-(pyrrolidin-2-yl)-4-(trifluoromethyl)phenol (CAS 1212975-93-3)
- Cefdinir Impurity 76 (CAS CATO-C4X-121076)
- 3-(7-(Difluoromethyl)-5-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid (CAS 1174869-32-9)
- 3-(1-Methylcyclopropyl)propanoic acid (CAS 87433-66-7)
- 1-(3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-4-amine trihydrochloride (CAS 2169997-57-1)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
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