Ethyl (4-(2,2,2-trifluoroethoxy)benzoyl)glycinate CAS 866153-60-8
| CAS No. | 866153-60-8 |
| Molecular Formula | C13H14F3NO4 |
| Molecular Weight | 305.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl (4-(2,2,2-trifluoroethoxy)benzoyl)glycinate.
Ethyl (4-(2,2,2-trifluoroethoxy)benzoyl)glycinate (CAS 866153-60-8), molecular formula C13H14F3NO4 and molecular weight 305.25 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl (4-(2,2,2-trifluoroethoxy)benzoyl)glycinate (C13H14F3NO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl (4-(2,2,2-trifluoroethoxy)benzoyl)glycinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14F3NO4 |
| Molecular Weight | 305.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(Bis(2,2,2-trifluoroethoxy)phosphoryl)acetic acid (CAS 209065-57-6)
- 4-(2,2,2-Trifluoroethoxy)phenylboronic Acid Pinacol Ester (CAS 886528-42-3)
- Tris[(trifluoroethoxy)methane] (CAS 58244-27-2)
- N-(4-(2,2,2-Trifluoroethoxy)benzyl)-1H-imidazole-1-carboxamide (CAS 1507835-05-3)
- 2,6-Bis(2,2,2-trifluoroethoxy)benzonitrile (CAS 93624-57-8)
- Ethyl 2-(2-{[(2,2,2-trifluoroethoxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate (CAS 1311314-73-4)
- 2-Phenyl-6-(2,2,2-trifluoroethoxy)pyrimidine-4-carboxylic acid (CAS 1708026-94-1)
- 3-Methyl-5-(2,2,2-trifluoroethoxy)isothiazole-4-sulfonyl chloride (CAS 111923-86-5)
Recommended Standards
- diethyl 2-methyl-6-(trifluoromethyl)pyridine-3,5-dicarboxylate (CAS 393-81-7)
- Ethyl 2-morpholin-4-yl-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 677706-89-7)
- Diethyl 2-(3-(trifluoromethyl)pyridin-2-yl)malonate (CAS 940933-26-6)
- Methyl (2S,4S)-4-[4-(trifluoromethoxy)phenoxy]-2-pyrrolidinecarboxylate (CAS 774576-25-9)
- 2-Propenoic acid, 2-methylpropyl ester, polymer with ethene (CAS 25068-58-0)
- (S)-4-Bromo-N-methyl-N-(3-methyl-1-(pyrrolidin-1-yl)butan-2-yl)benzamide (CAS 1380102-11-3)
- 4-Chloro-3-((2-chloro-4-nitrophenoxy)methyl)benzene-1-sulfonyl fluoride (CAS 30885-48-4)
- 4-Chloro-2-methyl-1,8-naphthyridine (CAS 1221272-96-3)
- 1-(4-Ethylphenyl)piperidine-4-carboxylic acid (CAS 1241894-78-9)
- 2-Fluoro-N-(4-fluorobenzyl)-5-methylaniline (CAS 1040050-77-8)
- Ophiobolin B (CAS 5601-74-1)
- 5,6,7,8-Tetrahydro-1H-benzo[4,5]thieno[2,3-c][1,2,6]thiadiazin-4(3H)-one 2-Oxide (CAS 77651-49-1)
- Quinine sulfate dihydrate (CAS 6119-70-6)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com