(E)-6-(4-fluorophenoxy)nicotinaldehyde O-(4-bromobenzyl) oxime CAS 866154-09-8
| CAS No. | 866154-09-8 |
| Molecular Formula | C19H14BrFN2O2 |
| Molecular Weight | 401.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-6-(4-fluorophenoxy)nicotinaldehyde O-(4-bromobenzyl) oxime.
CATO supplies (E)-6-(4-fluorophenoxy)nicotinaldehyde O-(4-bromobenzyl) oxime (CAS 866154-09-8), a certified reference material (molecular formula C19H14BrFN2O2, MW 401.23 g/mol) for analytical method development and quality control.
The molecular framework of (E)-6-(4-fluorophenoxy)nicotinaldehyde O-(4-bromobenzyl) oxime (C19H14BrFN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-6-(4-fluorophenoxy)nicotinaldehyde O-(4-bromobenzyl) oxime under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14BrFN2O2 |
| Molecular Weight | 401.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related E Standards
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Recommended Standards
- tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzylcarbamate (CAS 1798793-03-9)
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- Linagliptin Impurity 4 (CAS 2749405-42-1)
- (E)-4,6-Dichloro-3-((2-oxo-1-phenylpyrrolidin-3-ylidene)methyl)-1H-indole-2-carboxylic acid (CAS 166974-22-7)
- 4-(4-Methoxy-3-methylphenyl)-1,3-thiazol-2-amine (CAS 92388-06-2)
- N-(3-(1H-Imidazol-1-yl)propyl)-N-(6-chloro-4-methylbenzo[d]thiazol-2-yl)furan-2-carboxamide hydrochloride (CAS 1216645-19-0)
- 3-(Benzyloxy)cyclobutanone (CAS 30830-27-4)
- 3-[(4-fluorophenyl)amino]-4,5-dihydro-1h-pyrazol-5-one (CAS 324570-65-2)
- 2-(4-(Ethylthio)phenyl)pyridine (CAS 1443351-60-7)
- 2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-4-pyridylboronic acid pinacol ester (CAS 1257651-11-8)
- (1S,6R)-6-aminocyclohex-3-ene-1-carboxylic acid (CAS 54162-90-2)
- Methyl 4-(3,5-dimethylpiperazin-1-yl)benzoate (CAS 1035271-00-1)
- Mitiglinide Calcium Impurity 17 (CAS 70925-10-9)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
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