(4-(4-Nitrophenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone CAS 866154-42-9
| CAS No. | 866154-42-9 |
| Molecular Formula | C23H19F3N4O4 |
| Molecular Weight | 472.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (4-(4-Nitrophenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone (CAS 866154-42-9), a certified reference material (molecular formula C23H19F3N4O4, MW 472.42 g/mol) for analytical method development and quality control.
Structurally, (4-(4-Nitrophenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone (C23H19F3N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 472.42 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H19F3N4O4 |
| Molecular Weight | 472.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
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- 4-Nitrophenyl 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzene-1-sulfonate (CAS 338400-31-0)
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Recommended Standards
- Aciclovir Impurity 39 (CAS 1417988-85-2)
- 3-Amino-5-((2-((2-methoxyethyl)amino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yl)oxy)quinoxalin-2(1H)-one (CAS 939040-79-6)
- 1-Butyl-2-[(E)-[(2,6-dichlorophenyl)methylidene]amino]-4,5-diphenyl-1H-pyrrole-3-carbonitrile (CAS 478032-71-2)
- N-(2,6-Dichlorophenyl)-2-((5-((4-methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 477313-75-0)
- 4-Methylphenacyl thiocyanate (CAS 6097-27-4)
- 2-(tert-Butyl)-6-methoxyquinolin-8-amine (CAS 655250-13-8)
- 1-([1,1'-biphenyl]-4-yl)-2-aminoethan-1-ol (CAS 110826-96-5)
- 5-(Pyridin-4-yl)furan-2-carboxylic acid (CAS 216867-35-5)
- 5-Methyl-1,3-dioxan-2-one (CAS 87831-99-0)
- N-(2-Aminophenyl)-4-((4-methoxy-2H-indazol-2-yl)methyl)benzamide (CAS 920315-44-2)
- Eplerenone Impurity 34 (CAS CATO-C4X-163034)
- n-(3-Bromobenzyl)-1-(4-methylmorpholin-2-yl)methanamine (CAS 1491080-05-7)
- 1-(4-Bromophenyl)-1H-imidazole-4-carboxylic acid (CAS 445302-27-2)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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