(E)-[(4-Nitrophenyl)methoxy][1-(pyridin-2-yl)ethylidene]amine CAS 866154-49-6
| CAS No. | 866154-49-6 |
| Molecular Formula | C14H13N3O3 |
| Molecular Weight | 271.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-[(4-Nitrophenyl)methoxy][1-(pyridin-2-yl)ethylidene]amine.
(E)-[(4-Nitrophenyl)methoxy][1-(pyridin-2-yl)ethylidene]amine (CAS 866154-49-6) is a high-purity analytical reference standard with the molecular formula C14H13N3O3 and a molecular weight of 271.27 g/mol.
The molecular framework of (E)-[(4-Nitrophenyl)methoxy][1-(pyridin-2-yl)ethylidene]amine (C14H13N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13N3O3 |
| Molecular Weight | 271.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related E Standards
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- 1-[2-[(4-Nitrophenyl)methoxy]phenyl]ethanone (CAS 32437-48-2)
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- 6-(4-Nitrophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine (CAS 338791-45-0)
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- Methyl 2-(4-nitrophenyl)-2-phenylacetate (CAS 207500-10-5)
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Recommended Standards
- (2R,3R,4S,5R,6R)-2-(4-aminophenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 3398-86-5)
- (E)-[1-(Pyrazin-2-yl)ethylidene]amino 3-methoxybenzoate (CAS 866149-21-5)
- (2E)-3-[(2,3-Dimethylquinoxalin-6-yl)carbamoyl]prop-2-enoic acid (CAS 672949-88-1)
- (E)-[1-(Pyrazin-2-yl)ethylidene]amino 4-methoxybenzoate (CAS 861210-78-8)
- 3-Ethynylcyclohexan-1-one (CAS 54125-18-7)
- 4,4-Dimethyltetrahydro-2H-pyran-2-carbaldehyde (CAS 2766302-50-3)
- 8-Chloro-9H-purin-6-amine (CAS 28128-28-1)
- 2,3-Bis(4-fluorophenyl)propanoic acid (CAS 1017324-10-5)
- 7443-52-9 Cyclohexanol, trans- NSC-244887 NSC244887 trans-2-Methylcyclohexanol (CAS 7443-52-9)
- 1-[4-(aminomethyl)phenyl]-3,3-dimethylurea (CAS 164648-47-9)
- 2-(3,3-Difluoroazetidin-1-yl)-4-nitrobenzaldehyde 1713160-73-6 (CAS 1713160-73-6)
- 1-Nitro-3-(trifluoromethyl)dibenzo[b,e][1,4]dioxine (CAS 924843-88-9)
- Acarbose EP Impurity A (CAS 1013621-79-8)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
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