2-[(3-Chloro-4-fluorophenyl)amino]-2-(thiophen-2-yl)acetonitrile CAS 866154-51-0

Description

Compared with other compounds in its class, the molecular weight of 266.72 g/mol gives 2-[(3-Chloro-4-fluorophenyl)amino]-2-(thiophen-2-yl)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-[(3-Chloro-4-fluorophenyl)amino]-2-(thiophen-2-yl)acetonitrile (CAS 866154-51-0) is a high-purity analytical reference standard with the molecular formula C12H8ClFN2S and a molecular weight of 266.72 g/mol.

2-[(3-Chloro-4-fluorophenyl)amino]-2-(thiophen-2-yl)acetonitrile (C12H8ClFN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com