Ethyl 4-{[(2-fluorophenyl)methyl]amino}quinazoline-2-carboxylate CAS 866155-33-1
| CAS No. | 866155-33-1 |
| Molecular Formula | C18H16FN3O2 |
| Molecular Weight | 325.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 4-{[(2-fluorophenyl)methyl]amino}quinazoline-2-carboxylate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 4-{[(2-fluorophenyl)methyl]amino}quinazoline-2-carboxylate (CAS 866155-33-1) is a high-purity analytical reference standard with the molecular formula C18H16FN3O2 and a molecular weight of 325.34 g/mol.
The molecular framework of Ethyl 4-{[(2-fluorophenyl)methyl]amino}quinazoline-2-carboxylate (C18H16FN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 4-{[(2-fluorophenyl)methyl]amino}quinazoline-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16FN3O2 |
| Molecular Weight | 325.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 2-(4-Fluorophenyl)-6-(morpholin-4-yl)-3,4-dihydroquinazolin-4-one (CAS 691870-06-1)
- N-((1-(3-Fluorophenyl)-1H-tetrazol-5-yl)methyl)-3-phenylpropanamide (CAS 921102-26-3)
- Benzyl 2-(4-fluorophenyl)-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate (CAS 414910-19-3)
- 10-(4-Fluorophenyl)-10H-phenothiazine5,5-dioxide (CAS 2305615-55-6)
- 5-{[(2-fluorophenyl)methyl]sulfanyl}-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 439108-27-7)
- [Acetyl-[4-(4-Fluorophenyl)Phenyl]Amino] Hydrogen Sulfate (CAS 132884-69-6)
- 4-(4-Fluorophenyl)-2,6-diphenylpyridine (CAS 1498-83-5)
- 1-[2-(4-Fluorophenyl)-7-methylimidazo[1,2-a]pyrimidin-5-yl]-4-methylpiperazine (CAS 866050-72-8)
Recommended Standards
- 7-Fluoro-1-(4-methylbenzyl)-4-oxo-1,4-dihydroquinoline-3-carbohydrazide (CAS 478043-11-7)
- Famphur Impurity 6 (CAS 30978-90-6)
- 7-(Furan-2-yl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine (CAS 866132-17-4)
- JNJ-10198409 (CAS 627518-40-5)
- 5-Bromo-2-(2-fluorophenyl)-2H-1,2,3-triazol-4-amine (CAS 1779132-68-1)
- 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl 3,3-dimethylbutanoate (CAS 1894176-78-3)
- 3-[(1R)-1-aminoethyl]-6-chloro-1H-quinolin-2-one;hydrochloride (CAS 1887009-51-9)
- (S)-1-benzylpyrrolidine-3-carbonitrile (CAS 159063-16-8)
- (R)-Lorcaserin-D4DISCONTINUED. Please offer L469897 (CAS 1146440-33-6)
- 359810-48-3 5-(2-Bromo-4-methylphenyl)-2-furaldehyde DTXSID50358068 (CAS 359810-48-3)
- 2-Thiocarbamoyl-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 864958-51-0)
- Methyl (1aS,6aS)-4-methylenehexahydrocyclopropa[b]pyrrolizine-5a(3H)-carboxylate (CAS 2856022-72-3)
- 2-(4-Fluorophenoxy)-2-methylpropan-1-amine (CAS 1082423-80-0)
- Tripeptide-10 citrulline (CAS 960531-53-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com