N-(4-Fluorophenyl)-9H-fluorene-9-carboxamide CAS 866155-68-2
| CAS No. | 866155-68-2 |
| Molecular Formula | C20H14FNO |
| Molecular Weight | 303.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-Fluorophenyl)-9H-fluorene-9-carboxamide.
N-(4-Fluorophenyl)-9H-fluorene-9-carboxamide (CAS 866155-68-2) is a high-purity analytical reference standard with the molecular formula C20H14FNO and a molecular weight of 303.33 g/mol.
The molecular framework of N-(4-Fluorophenyl)-9H-fluorene-9-carboxamide (C20H14FNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-Fluorophenyl)-9H-fluorene-9-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14FNO |
| Molecular Weight | 303.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 6-(4-Fluorophenyl)-3-methyl-1-phenylpyrazolo[3,4-b]pyridine (CAS 1421680-21-8)
- 3-(4-Fluorophenyl)-6-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine (CAS 866132-31-2)
- N-((1-(3-Fluorophenyl)-1H-tetrazol-5-yl)methyl)cyclohexanecarboxamide (CAS 921166-93-0)
- 2-{[5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]amino}acetic acid (CAS 1082187-03-8)
- 1-(4-Fluorophenyl)-5-methyl-N-(thiazol-2-yl)-1H-1,2,3-triazole-4-carboxamide (CAS 915874-77-0)
- 2-(2-(4-Fluorophenyl)-5-(thiophen-3-yl)oxazol-4-yl)acetic acid (CAS 85162-11-4)
- 2-(5-(4-Fluorophenyl)isoxazol-3-yl)-N-(thiazol-2-yl)acetamide (CAS 952985-08-9)
- 6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-d]pyrimidine-2,4-diamine (CAS 95096-02-9)
Recommended Standards
- N-((1-Cyclohexyl-1H-tetrazol-5-yl)methyl)-4-fluorobenzamide (CAS 921103-99-3)
- Rosuvastatin Impurity 18 (CAS 712320-67-7)
- 801226-38-0 4-[3-(Furan-2-ylmethyl)-4-oxo-1,3-thiazolidin-2-yl]benzoic acid MFCD05813484 (CAS 801226-38-0)
- Methyl N-(2,5-dimethoxyphenyl)-N-(methylsulfonyl)glycinate (CAS 425607-54-1)
- (R)-1-(3-chlorophenyl)propane-1,3-diol (CAS 632327-18-5)
- N-[(1S,2S)-1,2,3,4-Tetrahydro-1-hydroxy-7-methoxy-2-naphthalenyl]-chloroacetamide (CAS 99833-89-3)
- AI-1 (CAS 75483-04-4)
- 2-(2-Acetyl-4-chlorophenoxy)-N-isopropylacetamide (CAS 923106-52-9)
- (1S,3S)-cyclopentane-1,3-diamine (CAS 1800560-58-0)
- 4-Demethylflucarbazone (CAS 749198-26-3)
- 5,8-difluoroisoquinoline (CAS 1895191-24-8)
- n-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)thiophene-2-carboxamide (CAS 941964-20-1)
- 754-34-7 1,1,2,2,3,3,3-Heptafluoro-1-iodopropane Heptafluoro-1-iodopropane Propane, heptafluoro-1-iodo- Propane, 1,1,1,2,2,3,3-heptafluoro-3-iodo- EINECS 212-045-5 1,1,1,2,2,3,3-Heptafluoro-3-iodopropane Heptafluoropropyl iodide 1-Iodoheptafluoropropane 1-Iodoperfluoropropane NSC 66409 Perfluoropropyl iodide 1-Perfluoropropyl iodide (CAS 754-34-7)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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