4-Methyl-5-[2-(4-phenylpiperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one CAS 866156-82-3
| CAS No. | 866156-82-3 |
| Molecular Formula | C22H26N4O2 |
| Molecular Weight | 378.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methyl-5-[2-(4-phenylpiperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one.
4-Methyl-5-[2-(4-phenylpiperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one (CAS 866156-82-3), molecular formula C22H26N4O2 and molecular weight 378.47 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 4-Methyl-5-[2-(4-phenylpiperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Methyl-5-[2-(4-phenylpiperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H26N4O2 |
| Molecular Weight | 378.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related Methyl Standards
- 2-(4-Phenylpiperazin-1-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 524062-32-6)
- 2-((5-(4-Phenylpiperazin-1-yl)-1,3,4-thiadiazol-2-yl)thio)-N-propylacetamide (CAS 1105226-20-7)
- N-(3-(4-Phenylpiperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-5-carboxamide (CAS 1211262-96-2)
- 1-{[2-(4-phenylpiperazin-1-yl)-1,3-thiazol-5-yl]methyl}-1H-indole (CAS 439097-15-1)
- 1-{5-[(4-phenylpiperazin-1-yl)methyl]-1,3-thiazol-2-yl}-1H-indole (CAS 860650-03-9)
- 2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylate (CAS 566140-89-4)
- 1-(4-Phenylpiperazin-1-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one (CAS 551920-99-1)
- 7-Phenyl-2-(4-phenylpiperazin-1-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1226457-63-1)
Recommended Standards
- 4-[4-(tert-Butyl)benzoyl]-N-[3-(1H-imidazol-1-yl)propyl]-1H-pyrrole-2-carboxamide (CAS 439111-49-6)
- 5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide (CAS 959626-45-0)
- 4-(4-(Dimethylamino)phenyl)-N-(3,5-dimethylphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 537679-57-5)
- Methyl 2-({2-phenylthieno[3,2-d]pyrimidin-4-yl}sulfanyl)benzoate (CAS 692738-32-2)
- n-(3-Chlorobenzyl)-2-methylbutan-2-amine (CAS 932261-67-1)
- N-(4,5,6,7-Tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)thiophene-3-carboxamide hydrochloride (CAS 1421457-85-3)
- 2-((4-(N-(6-methoxypyridazin-3-yl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 13010-46-3)
- (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)prop-2-en-1-amine hydrochloride (CAS 1213150-66-3)
- 3'-Isopropoxy-[1,1'-biphenyl]-4-thiol (CAS 1443352-72-4)
- Finerenone Impurity 200 (CAS CATO-C4X-2880200)
- 2-Amino-2-(3-bromophenyl)acetamide (CAS 1105679-26-2)
- L-Cyclopropylglycine (CAS 49606-99-7)
- 7-Boc-3-bromo-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine (CAS 723286-80-4)
- Compstatin control peptide (CAS 301544-78-5)
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