1-[4-(Pyrazin-2-yloxy)phenyl]propan-1-one CAS 866156-99-2

Purity 97%+In StockPharmaceutical Standards
CAS No.866156-99-2
Molecular FormulaC13H12N2O2
Molecular Weight228.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[4-(Pyrazin-2-yloxy)phenyl]propan-1-one CAS 866156-99-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[4-(Pyrazin-2-yloxy)phenyl]propan-1-one.

CATO supplies 1-[4-(Pyrazin-2-yloxy)phenyl]propan-1-one (CAS 866156-99-2), a certified reference material (molecular formula C13H12N2O2, MW 228.25 g/mol) for analytical method development and quality control.

The molecular framework of 1-[4-(Pyrazin-2-yloxy)phenyl]propan-1-one (C13H12N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-[4-(Pyrazin-2-yloxy)phenyl]propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H12N2O2
Molecular Weight228.25 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms2

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