N-(3-(pyrazin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide CAS 866157-13-3
| CAS No. | 866157-13-3 |
| Molecular Formula | C18H12F3N3O2 |
| Molecular Weight | 359.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies N-(3-(pyrazin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide (CAS 866157-13-3), a certified reference material (molecular formula C18H12F3N3O2, MW 359.30 g/mol) for analytical method development and quality control.
N-(3-(pyrazin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide (C18H12F3N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures N-(3-(pyrazin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12F3N3O2 |
| Molecular Weight | 359.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-((4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-fluorophenyl)acetamide (CAS 573930-79-7)
- 2-((4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 578001-34-0)
- 2-((4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 586997-18-4)
- (4-(Pyrazin-2-yloxy)piperidin-1-yl)(1-(thiophen-2-yl)cyclopentyl)methanone (CAS 1421493-68-6)
- Pyrazin-2-yl(9-(thiazol-2-ylmethyl)-3,9-diazaspiro[5.5]undecan-3-yl)methanone (CAS 959482-29-2)
- (Z)-[1-(Pyrazin-2-yl)ethylidene]amino 3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 866050-54-6)
- N-(1-(3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)thiophene-3-carboxamide (CAS 1396856-49-7)
- 4-(2,6-Di(pyrazin-2-yl)pyridin-4-yl)benzoic acid (CAS 1239444-46-2)
Recommended Standards
- Ethyl 2-(hydrazinecarbonyl)-3-((3-(trifluoromethyl)phenyl)carbamoyl)cyclopropane-1-carboxylate (CAS 318237-91-1)
- tert-Butyl 2,6-dioxo-4-(4-(trifluoromethyl)phenyl)-1,3-oxazinane-3-carboxylate (CAS 886362-59-0)
- 6-Oxo-N,1-diphenyl-4-(trifluoromethyl)-1,6-dihydropyridazine-3-carboxamide (CAS 477859-50-0)
- Methyl2-(((benzyloxy)carbonyl)amino)-2-(diethoxyphosphoryl)acetate (CAS 114684-69-4)
- 2-(Chloromethyl)-5-cyano-3-(difluoromethyl)-4-(trifluoromethyl)pyridine (CAS 1804699-23-7)
- Acetylthiomethyl-diphenylphosphine borane complex (CAS 446822-71-5)
- 1-Methyloctahydro-1H-pyrrolo[2,3-b]pyridine (CAS 1505259-64-2)
- N-Methyl-1-(4-methylphenyl)-4-nitro-1H-pyrazol-5-amine (CAS 318238-12-9)
- 5-(Chloromethyl)picolinonitrile hydrochloride (CAS 1225380-31-3)
- 4-(2-Aminoethoxy)-1,2,5-oxadiazol-3-amine (CAS 313549-19-8)
- (2-Ethylphenyl)(furan-2-yl)methanol (CAS 60907-94-0)
- 3-(2-Methoxybenzyl)azetidin-3-ol (CAS 1524198-63-7)
- 1-(3-(Dimethylamino)propyl)-1H-benzo[d]imidazol-5-amine trihydrochloride (CAS 1245569-20-3)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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