5-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine CAS 866319-01-9
| CAS No. | 866319-01-9 |
| Molecular Formula | C10H19FN2Si |
| Molecular Weight | 214.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine (CAS 866319-01-9), a certified reference material (molecular formula C10H19FN2Si, MW 214.36 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine substitution, 5-fluoro-3-(2-trimethylsilylethynyl)pyridin-2-amine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H19FN2Si |
| Molecular Weight | 214.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- N-hydroxy-dodecanamidine (CAS 95500-20-2)
- 1-(Thiomorpholinomethyl)cyclohexan-1-amine (CAS 1042633-26-0)
- 1-Amino-3-phenylbutan-2-ol (CAS 133562-22-8)
- 7-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 1186334-62-2)
- 1,2,5-Trimethyl-N-pentylpiperidin-4-amine (CAS 1218562-42-5)
- 3-[3-(tert-Butyl)phenoxy]pyrrolidine hydrochloride (CAS 1220037-34-2)
- 6-Methoxypyridine-3-carbothioanide (CAS 175277-49-3)
- D-4-Hydroxyphenyl-d4-alanine (CAS 944386-47-4)
- CAS 68261-19-8 (CAS 68261-19-8)
- 3-(Difluoromethyl)-6-fluoro-5-nitropyridin-2-amine (CAS 1806830-88-5)
- 1-(3-Methoxypropyl)-1h-pyrazol-3-amine (CAS 1179235-39-2)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com