2,4-Dichloro-6-(methylthio)pyridine CAS 86634-72-2

Purity 97%+In StockPharmaceutical Standards
CAS No.86634-72-2
Molecular FormulaC6H5Cl2NS
Molecular Weight194.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,4-Dichloro-6-(methylthio)pyridine CAS 86634-72-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Dichloro-6-(methylthio)pyridine.

2,4-Dichloro-6-(methylthio)pyridine (CAS 86634-72-2), molecular formula C6H5Cl2NS and molecular weight 194.08 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,4-Dichloro-6-(methylthio)pyridine (C6H5Cl2NS) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H5Cl2NS
Molecular Weight194.08 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

Related Dichloro Standards

Recommended Standards

Why CATO?