6-(Benzofuran-2-yl)-4-(trifluoromethyl)pyridazin-3(2H)-one CAS 866474-43-3
| CAS No. | 866474-43-3 |
| Molecular Formula | C13H7F3N2O2 |
| Molecular Weight | 280.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(Benzofuran-2-yl)-4-(trifluoromethyl)pyridazin-3(2H)-one.
CATO supplies 6-(Benzofuran-2-yl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 866474-43-3), a certified reference material (molecular formula C13H7F3N2O2, MW 280.20 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-(Benzofuran-2-yl)-4-(trifluoromethyl)pyridazin-3(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(Benzofuran-2-yl)-4-(trifluoromethyl)pyridazin-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H7F3N2O2 |
| Molecular Weight | 280.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Benzofuran Standards
- 4-(Benzofuran-2-carboxamido)benzoic acid (CAS 308298-71-7)
- 9-(Benzofuran-2-yl)-3-methyl-3-azaspiro[5.5]undec-8-ene (CAS 918650-92-7)
- 2-(Benzofuran-2-yl)-3-hydroxy-4H-chromen-4-one (CAS 67261-94-3)
- N-((5-(Benzofuran-2-yl)isoxazol-3-yl)methyl)cyclopropanecarboxamide (CAS 1105205-53-5)
- 3-((Benzofuran-2-ylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one (CAS 135525-72-3)
- 4-(Benzofuran-2-yl)-5-hydroxyisoquinolin-1(2H)-one (CAS 656234-39-8)
- 4-(Benzofuran-2-ylselanyl)butanoic acid (CAS 65320-28-7)
- (5-(Benzofuran-2-yl)isoxazol-3-yl)methyl (Z)-but-2-enoate (CAS 1212764-88-9)
Recommended Standards
- 3-(4-Hydroxyphenoxy)-5-(trifluoromethyl)picolinonitrile (CAS 338791-69-8)
- 7'-Bromo-2',3'-dihydro-1'H-spiro[cyclohexane-1,4'-isoquinoline] (CAS 626603-70-1)
- 2-(4-Bromophenyl)-2-azaspiro[4.4]nonane (CAS 61343-32-6)
- Bis((2-chlorothiazol-5-yl)methyl)amine (CAS 434902-57-5)
- tert-Butyl (2-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)carbamate (CAS 2609867-07-2)
- (E)-1,3-Dimethyl-2-(2-(thiophen-2-yl)vinyl)-2,3-dihydro-1H-imidazole (CAS 791586-11-3)
- 11-(Chloromethyl)-12-formyl-13-oxo-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2,4,6,9,11-pentaene-10-carbonitrile (CAS 571155-05-0)
- 1-(2,4-Difluorophenyl)pyrrolidine-2,5-dione (CAS 124704-70-7)
- 5-(Trifluoromethyl)benzofuran (CAS 741290-20-0)
- Alaninamide, L-threonyl-2-[(1Z)-1-amino-1-propen-1-yl]-4-oxazolecarbonyl-2,3-didehydroalanyl-3-methyl-L-threonyl-2-(1-aminoethenyl)-5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-6-[2-(1-aminoethenyl)-4-oxazolyl]-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (7→1)-lactam (CAS 158792-27-9)
- N1,N4-dibutylpiperazine-1,4-dicarboxamide (CAS 6442-90-6)
- 4-Iododiphenylmethane (CAS 35444-94-1)
- 4'-Chloro-3,4,5-trimethoxy-1,1'-biphenyl (CAS 1032506-57-2)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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