2,4-Diamino-N-(tert-butyl)quinazoline-6-sulfonamide CAS 86651-16-3
| CAS No. | 86651-16-3 |
| Molecular Formula | C12H17N5O2S |
| Molecular Weight | 295.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Diamino-N-(tert-butyl)quinazoline-6-sulfonamide (CAS 86651-16-3) is a high-purity analytical reference standard with the molecular formula C12H17N5O2S and a molecular weight of 295.36 g/mol.
The molecular framework of 2,4-Diamino-N-(tert-butyl)quinazoline-6-sulfonamide (C12H17N5O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,4-Diamino-N-(tert-butyl)quinazoline-6-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17N5O2S |
| Molecular Weight | 295.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Diamino Standards
- 2,4-Diamino-N-(sec-butyl)quinazoline-6-sulfonamide (CAS 86651-19-6)
- 2,4-Diamino-N-butylquinazoline-6-sulfonamide (CAS 21811-08-5)
- 4,6-Diamino-1-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1h-pyrrolo[2,3-b]pyridine-5-carbonitrile (CAS 124476-83-1)
- 2,3-Diamino-N-(4-(trifluoromethyl)phenyl)benzamide (CAS 1421933-32-5)
- 1,6-Diamino-4-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 339248-22-5)
- 2,4-Diamino-6-((3,4-dichlorophenyl)amino)pyrimidine-5-carbonitrile (CAS 7357-32-6)
- 1,6-Diamino-4-(2-nitrophenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 153334-66-8)
- 4,6-Diamino-2-((o-tolyloxy)methyl)-2,3-dihydrofuro[2,3-b]pyridine-5-carbonitrile (CAS 343374-98-1)
Recommended Standards
- 2-(tert-Butylsulfonyl)-2-[2-(4-methoxyphenyl)hydrazono]acetonitrile (CAS 241127-19-5)
- 2-Amino-N,4-diphenylthiazole-5-carboxamide (CAS 300815-19-4)
- 2-(tert-Butylsulfonyl)-2-[2-(3-methoxyphenyl)hydrazono]acetonitrile (CAS 241127-20-8)
- 3-(4-(2-Hydroxyethyl)piperazin-1-yl)benzo[d]isothiazole 1,1-dioxide (CAS 421570-23-2)
- 1-(5-Chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazol-5-ol (CAS 189005-07-0)
- 4-Chlorocyclohexane-1-carboxylic acid (CAS 56447-20-2)
- 1-(1H-imidazole-5-carbonyl)pyrrolidine-3-carboxylic acid (CAS 1488310-52-6)
- 2-Bromo-6-chloro-3-(difluoromethyl)-5-methoxypyridine (CAS 1805350-31-5)
- 1-[(3-Bromophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240567-36-5)
- 4-{[(1-Methyl-1H-benzimidazol-2-yl)methyl]amino}benzoic Acid (CAS 328559-27-9)
- (S)-3-Amino-5-(methylthio)pentanoic Acid (CAS 1217975-36-4)
- 1-Chloro-3-methoxypropane (CAS 36215-07-3)
- 7-Bromo-5-fluorochroman-3-amine (CAS 1337386-56-7)
- Glucagon receptor antagonist I (CAS 438618-32-7)
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