Tigecycline Impurity 20 CAS 866602-58-6
| CAS No. | 866602-58-6 |
| Molecular Formula | C29H39N5O9 |
| Molecular Weight | 601.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tigecycline Impurity 20.
Tigecycline Impurity 20 (CAS 866602-58-6) is a certified pharmaceutical impurity reference standard with the molecular formula C29H39N5O9 and a molecular weight of 601.65 g/mol.
Tigecycline Impurity 20 (C29H39N5O9) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H39N5O9 |
| Molecular Weight | 601.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Tigecycline Standards
- Tigecycline Impurity 27 (CAS CATO-C4X-186027)
- Tigecycline Impurity 28 (CAS CATO-C4X-186028)
- Tigecycline Impurity 21 (CAS CATO-C4X-186021)
- Tigecycline Impurity 14 (CAS CATO-C4X-186014)
- Tigecycline Impurity 15 (CAS CATO-C4X-186015)
- Tigecycline-d9 (CAS 2699607-86-6)
- Tigecycline Impurity 13 (CAS CATO-C4X-186013)
- Tigecycline Impurity 11 (CAS CATO-C4X-186011)
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