Methyl 3-amino-6-bromo-5-chloropicolinate CAS 866775-12-4
| CAS No. | 866775-12-4 |
| Molecular Formula | C7H6BrClN2O2 |
| Molecular Weight | 265.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3-amino-6-bromo-5-chloropicolinate.
Methyl 3-amino-6-bromo-5-chloropicolinate (CAS 866775-12-4) is a high-purity analytical reference standard with the molecular formula C7H6BrClN2O2 and a molecular weight of 265.49 g/mol.
The molecular framework of Methyl 3-amino-6-bromo-5-chloropicolinate (C7H6BrClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 3-amino-6-bromo-5-chloropicolinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BrClN2O2 |
| Molecular Weight | 265.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- Methyl 3-amino-2-bromo-6-chloroisonicotinate (CAS 1073182-61-2)
- Methyl 3-amino-4-bromo-6-chloropicolinate (CAS 1073182-89-4)
- Methyl 5-amino-6-bromo-2-chloronicotinate (CAS 1820707-39-8)
- Methyl 6-amino-5-bromo-2-chloronicotinate (CAS 2814523-39-0)
- Methyl 6-amino-5-bromo-3-chloropicolinate (CAS 577691-68-0)
- Methyl 2-amino-5-fluoro-4-((trimethylsilyl)ethynyl)benzoate (CAS 2537749-39-4)
- 2-((5-Amino-4-phenylthiazol-2-yl)thio)acetamide (CAS 1021223-06-2)
- (S)-2-Amino-N-isopropyl-3-methyl-N-(2-oxo-2-(1H-pyrrol-2-yl)ethyl)butanamide (CAS 1354009-26-9)
Recommended Standards
- Magnesium aluminum zirconium oxide, 99% (metals basis excluding Ca) Ca 0.1-1% (CAS 53169-11-2)
- Methyl 3-bromo-5-chloro-2-hydroxybenzoate (CAS 4068-71-7)
- 5-Bromo-4-chloro-2-methoxybenzoic acid (CAS 95383-17-8)
- Methyl 5-bromo-4-chloro-2-hydroxybenzoate (CAS 55488-81-8)
- 2-Phenyl-1-(pyridin-4-yl)-1H-imidazole-4-carboxylic acid (CAS 787563-21-7)
- 2-Chloro-N-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine (CAS 1375301-41-9)
- 9,9'-Spirobi[fluoren]-2-yldiphenylphosphine oxide (CAS 1125547-88-7)
- Tetrakis(2-(dodecyldisulfanyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate (CAS 2566523-07-5)
- Benzyl (1-(2-aminoacetyl)pyrrolidin-3-yl)(isopropyl)carbamate (CAS 1353954-17-2)
- 2-Bromo-4-iodo-3-nitropyridine (CAS 1807213-37-1)
- Methyl (R)-2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate (CAS 56877-38-4)
- 6-Amino-5-chloro-2-(difluoromethyl)pyridine-3-sulfonamide (CAS 1804953-30-7)
- 3-[(1E)-1-[2-(6-Chloropyridin-2-yl)hydrazin-1-yl]-2-(2,4-dichlorophenoxy)ethylidene]-1-phenylurea (CAS 338418-66-9)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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