5-(2-Fluorobenzyl)-3-(4-methoxyphenyl)-8-methyl-5H-pyrazolo[4,3-c]quinoline CAS 866809-58-7
| CAS No. | 866809-58-7 |
| Molecular Formula | C25H20FN3O |
| Molecular Weight | 397.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(2-Fluorobenzyl)-3-(4-methoxyphenyl)-8-methyl-5H-pyrazolo[4,3-c]quinoline (C25H20FN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5-(2-Fluorobenzyl)-3-(4-methoxyphenyl)-8-methyl-5H-pyrazolo[4,3-c]quinoline (CAS 866809-58-7), a certified reference material (molecular formula C25H20FN3O, MW 397.44 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2-Fluorobenzyl)-3-(4-methoxyphenyl)-8-methyl-5H-pyrazolo[4,3-c]quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H20FN3O |
| Molecular Weight | 397.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorobenzyl Standards
- 5-(2-Fluorobenzyl)-8-methoxy-3-(p-tolyl)-5H-pyrazolo[4,3-c]quinoline (CAS 866341-39-1)
- (4-((4-Fluorobenzyl)oxy)-1-(4-fluorophenyl)-1H-pyrazol-3-yl)(piperidin-1-yl)methanone (CAS 1185099-03-9)
- 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(pyridin-4-yl)pyrimidin-4-amine (CAS 402595-29-3)
- 2-[4-(4-Fluorobenzyl)-1-piperidinyl]-2-oxo-N-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide (CAS 496054-87-6)
- 4-(4-Fluorobenzyl)-3-((3-methoxybenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 294853-33-1)
- 2-Ethyl-5-((4-fluorobenzyl)thio)-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline (CAS 1221715-40-7)
- 2-((4-Fluorobenzyl)thio)-4,5-diphenyl-1-(prop-2-yn-1-yl)-1H-imidazole (CAS 339277-63-3)
- 13-((4-Fluorobenzyl)oxy)-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-dione (CAS 478029-52-6)
Recommended Standards
- 4-(((4'-Methoxy-[1,1'-biphenyl])-4-sulfonamido)methyl)benzoic acid (CAS 885269-44-3)
- 4-(((4-(O-tolyloxy)phenyl)sulfonamido)methyl)benzoic acid (CAS 885268-78-0)
- Ethyl 2-(2-amino-3-(1H-indol-3-yl)propanamido)-3-(4-fluorophenyl)propanoate (CAS 4615-99-0)
- 3-[benzyl(4-methoxyphenyl)sulfamoyl]benzoic acid (CAS 750610-53-8)
- 3-(1H-Pyrrol-2-yl)-1H-pyrazole (CAS 1019010-39-9)
- 2-((2-Oxo-2-(piperidin-1-yl)ethyl)thio)benzoic acid (CAS 354128-84-0)
- Quinoline-2-Carboxylic Acid (CAS 93-10-7)
- Benzyl 2-amino-4-methylthiazole-5-carboxylate (CAS 692745-02-1)
- 2-((3,4,5-Trimethyl-1H-pyrrol-2-yl)methylene)malononitrile (CAS 59435-04-0)
- Narciclasine (CAS 29477-83-6)
- 3-Chloro-2-hydroxy-N-(2-(methacryloyloxy)ethyl)-N,N-dimethylpropan-1-aminium chloride (CAS 58564-96-8)
- N-(4-Amino-2,6-dichlorophenyl)methanesulfonamide (CAS 926265-82-9)
- [1-(hydroxymethyl)-4-methylene-cyclohexyl]methanol (CAS 1354932-12-9)
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