Varenicline dihydrochloride - Chantix CAS 866823-63-4
| CAS No. | 866823-63-4 |
| Molecular Formula | C13H13N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Varenicline dihydrochloride - Chantix.
CATO supplies Varenicline dihydrochloride - Chantix (CAS 866823-63-4), a certified reference material (molecular formula C13H13N3HCl, MW 247.73 g/mol) for analytical method development and quality control.
Structurally, Varenicline dihydrochloride - Chantix (C13H13N3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 247.73 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Varenicline dihydrochloride - Chantix meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13N3 2*HCl |
| Molecular Weight | 247.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Varenicline Standards
- Varenicline Impurity 28 (CAS 1026685-55-1)
- Varenicline Impurity 6 (CAS 116601-09-3)
- Varenicline Impurity 22 (CAS 1213781-59-9)
- Varenicline Impurity 31 (CAS 1333145-89-3)
- Varenicline Impurity 16 (CAS 1337563-47-9)
- Varenicline Impurity 70 (CAS 1337563-47-9 (free base))
- Varenicline Impurity 23 (CAS 1350219-74-7)
- Varenicline-d4 (CAS 2183239-01-0)
Recommended Standards
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- N-(2-(Methylthio)benzo[d]thiazol-6-yl)-3-(thiophen-2-yl)acrylamide (CAS 477243-01-9)
- Phenylcopper(III) ditrifluoromethanesulfonate (CAS 1360895-43-7)
- 1-(4-((2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine (CAS 89929-33-9)
- 6-(Methylcarbamoyl)pyridine-3-boronic Acid Pincol Ester (CAS 945863-21-8)
- 3-(4-Ethylphenyl)pentan-3-ol (CAS 1247388-02-8)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
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