3-(4-Benzylpiperazin-1-yl)-N-(4-chlorophenyl)but-2-enamide CAS 867159-68-0
| CAS No. | 867159-68-0 |
| Molecular Formula | C21H24ClN3O |
| Molecular Weight | 369.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(4-Benzylpiperazin-1-yl)-N-(4-chlorophenyl)but-2-enamide (CAS 867159-68-0), molecular formula C21H24ClN3O and molecular weight 369.89 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(4-Benzylpiperazin-1-yl)-N-(4-chlorophenyl)but-2-enamide (C21H24ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-(4-Benzylpiperazin-1-yl)-N-(4-chlorophenyl)but-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H24ClN3O |
| Molecular Weight | 369.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Benzylpiperazin Standards
- (4-Benzylpiperazin-1-yl)(3,5-dinitrophenyl)methanone (CAS 289476-03-5)
- 1-(4-Benzylpiperazin-1-yl)-2,2-diphenylethan-1-one (CAS 16870-70-5)
- 2-(4-Benzylpiperazin-1-yl)-N'-(1-(4-fluorophenyl)ethylidene)acetohydrazide (CAS 303107-62-2)
- [[2-(4-Benzylpiperazin-1-yl)-2-oxoethyl](phenyl)-amino]acetic acid (CAS 1142211-73-1)
- 2-(4-Benzylpiperazin-1-yl)-3-chloronaphthalene-1,4-dione (CAS 104309-93-5)
- 2-(4-Benzylpiperazin-1-yl)-4-oxo-4-(p-tolyl)butanoic acid (CAS 329079-61-0)
- N-{4-[(4-benzylpiperazin-1-yl)sulfonyl]phenyl}acetamide (CAS 294885-65-7)
- 2-(4-Benzylpiperazin-1-yl)-N-(4-butylphenyl)acetamide (CAS 303091-32-9)
Recommended Standards
- 2-(4-(4-Chlorobenzyl)piperazin-1-yl)-1-(indolin-1-yl)ethan-1-one (CAS 240127-55-3)
- 4-((3-Chlorophenyl)thio)-2-(methylthio)-6-phenylpyrimidine-5-carbonitrile (CAS 341965-69-3)
- 1-Butyl-3-(2-chloro-6-(3-methyl-1H-indol-1-yl)benzyl)urea (CAS 866042-64-0)
- 4-((4-Chlorophenyl)thio)-2-(methylthio)-6-phenylpyrimidine-5-carbonitrile (CAS 341965-68-2)
- 3-[4-[2-(2-aminoethoxy)ethyl]-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2759185-15-2)
- 1-(1-(Thiazol-2-yl)ethyl)piperidin-4-amine hydrochloride (CAS 1185311-19-6)
- Decylpyridinium bromide (CAS 2534-65-8)
- 5,11-Dihexyl-5,11-dihydroindolo[3,2-b]carbazole (CAS 924648-25-9)
- 4-[(difluoromethyl)sulfanyl]aniline hydrochloride (CAS 477593-83-2)
- 3-methyl-7H-pyrazolo[3,4-b]pyridine-5-carbohydrazide (CAS 1208632-34-1)
- Ethyl 5-amino-4-chloro-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate (CAS 1427014-18-3)
- 2-Oxoethyl (4-(((R)-3-aminobutyl)amino)-2-((6-guanidinohexyl)amino)butyl)carbamate (CAS 170368-04-4)
- Trazodone impurity 56 (CAS CATO-C4X-177256)
- Uremic Pentapeptide (CAS 71494-20-7)
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