2-Bromo-6-chloro-3-methylpyridine CAS 867377-03-5
| CAS No. | 867377-03-5 |
| Molecular Formula | C6H5BrClN |
| Molecular Weight | 206.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 206.47 g/mol gives 2-Bromo-6-chloro-3-methylpyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Bromo-6-chloro-3-methylpyridine (CAS 867377-03-5) is a high-purity analytical reference standard with the molecular formula C6H5BrClN and a molecular weight of 206.47 g/mol.
Based on its molecular formula C6H5BrClN, 2-Bromo-6-chloro-3-methylpyridine contains a nitrile group, chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 206.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-6-chloro-3-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BrClN |
| Molecular Weight | 206.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-(chloromethyl)pyridine (CAS 1001463-32-6)
- 5-Bromo-4-chloro-2-methylpyridine (CAS 1003711-85-0)
- 2-Bromo-4-chloro-5-methylpyridine (CAS 1033203-40-5)
- 3-Bromo-4-(chloromethyl)pyridine (CAS 1060802-26-7)
- 4-Bromo-3-(chloromethyl)pyridine (CAS 1060808-80-1)
- 3-Bromo-4-chloro-2-methylpyridine (CAS 1188023-70-2)
- 4-Bromo-3-chloro-2-methylpyridine (CAS 1188140-52-4)
- 2-Bromo-4-chloro-6-methylpyridine (CAS 1206249-38-8)
Recommended Standards
- 2-Bromo-6-(chloromethyl)pyridine (CAS 727356-19-6)
- 2-Bromo-6-chloroaniline (CAS 59772-49-5)
- 2-Bromo-5-chloroaniline (CAS 823-57-4)
- 2-Chloro-3-methyl-5-bromopyridine (CAS 29241-60-9)
- 8-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-2-one (CAS 1314934-34-3)
- 6,7-Dihydro-5H-cyclopenta[d]pyrimidine (CAS 5661-00-7)
- Golgicide A-1 (CAS 1394285-49-4)
- 6-HExyloxy-2-hexylsulfanyl-pyrimidin-4-ol (CAS 1892575-76-6)
- n-[(5-methylpyridin-2-yl)methylidene]hydroxylamine (CAS 1300609-97-5)
- Phosphate ion in water quality (CAS CATO-CQCM102191)
- (E)-5-(3-Hydroxyprop-1-en-1-yl)-2-methoxyphenol (CAS 344402-10-4)
- 2-[1-(2-Methylpropyl)-1H-pyrazol-4-yl]cyclopropane-1-carboxylic acid (CAS 1707369-55-8)
- 2,4-Dichloro-6-(trifluoromethyl)aniline (CAS 62593-17-3)
- Insulin Glulisine (CAS 207748-29-6)
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