3-((2-Fluorobenzyl)oxy)propanoic acid CAS 868277-59-2
| CAS No. | 868277-59-2 |
| Molecular Formula | C10H11FO3 |
| Molecular Weight | 198.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-((2-Fluorobenzyl)oxy)propanoic acid (C10H11FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3-((2-Fluorobenzyl)oxy)propanoic acid (CAS 868277-59-2), molecular formula C10H11FO3 and molecular weight 198.19 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((2-Fluorobenzyl)oxy)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11FO3 |
| Molecular Weight | 198.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluorobenzyl Standards
- Methyl 2-((2-fluorobenzyl)oxy)acetate (CAS 1342876-45-2)
- Methyl (4-fluorobenzyl)carbamimidothioate (CAS 1011347-39-9)
- 2-((3-Fluorobenzyl)amino)butan-1-ol (CAS 1038259-55-0)
- 1-((3-Fluorobenzyl)amino)-2-methylpropan-2-ol (CAS 1179941-00-4)
- 1-((2-Fluorobenzyl)amino)-2-methylpropan-2-ol (CAS 1184377-47-6)
- 2-(Ethyl(4-fluorobenzyl)amino)ethanol (CAS 1247457-92-6)
- 2-(Ethyl(2-fluorobenzyl)amino)ethanol (CAS 1249305-67-6)
- 2-(Ethyl(3-fluorobenzyl)amino)ethanol (CAS 1250716-65-4)
Recommended Standards
- 2-methoxy-5-(trifluoromethyl)pyridin-3-amine (CAS 944900-42-9)
- 3-(2-Fluoro-4-hydroxyphenyl)-1,1-dimethylurea (CAS 821765-73-5)
- 2-Fluoro-9H-fluoren-9-one (CAS 343-01-1)
- 3-(2-Fluoro-4-methoxyphenyl)propanoic acid (CAS 852181-15-8)
- Tert-butyl (R)-2-((R)-sec-butyl)piperazine-1-carboxylate (CAS 1932414-73-7)
- 2-(4-Isopropylphenyl)-2-oxoacetic acid (CAS 51208-83-4)
- 2-(1-(2-Methoxyethyl)-1H-pyrazol-4-yl)ethan-1-amine (CAS 1343369-80-1)
- 6-(Chloromethyl)-3-methoxyquinoline (CAS 1051316-29-0)
- 3-[(Diethylamino)methyl]-1-(4-methoxyphenyl)-4-phenylazetidin-2-one (CAS 478049-90-0)
- 1-(BENZO[D][1,3]DIOXOL-6-YL)-2-NITROETHANOL (CAS 40288-64-0)
- 2,2,2-Trifluoroethanamine hydrochloride (CAS 373-88-6)
- 1,1-Dibromospiro[2.3]hexane (CAS 33669-81-7)
- Butylphthalide Impurity 70 (CAS 102126-70-5)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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