n-(5-Chloropyridin-2-yl)-2,2-dimethylpropanamide CAS 86847-83-8
| CAS No. | 86847-83-8 |
| Molecular Formula | C10H13ClN2O |
| Molecular Weight | 212.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of n-(5-Chloropyridin-2-yl)-2,2-dimethylpropanamide (C10H13ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies n-(5-Chloropyridin-2-yl)-2,2-dimethylpropanamide (CAS 86847-83-8), a certified reference material (molecular formula C10H13ClN2O, MW 212.68 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), n-(5-Chloropyridin-2-yl)-2,2-dimethylpropanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13ClN2O |
| Molecular Weight | 212.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related n Standards
- 1-(6-Chloropyridin-2-yl)piperidin-4-ol (CAS 1220036-23-6)
- 4-((2-Chloropyridin-3-yl)methyl)morpholine (CAS 1250205-26-5)
- 1-((6-Chloropyridin-3-yl)methyl)pyrrolidin-3-ol (CAS 1343606-51-8)
- 3-((3-Chloropyridin-4-yl)methyl)pyrrolidin-3-ol (CAS 1479230-02-8)
- N-(4-chloropyridin-2-yl)pivalamide (CAS 188577-70-0)
- (R)-1-((6-chloropyridin-3-yl)methyl)pyrrolidin-3-ol (CAS 764715-23-3)
- (S)-1-((6-chloropyridin-3-yl)methyl)pyrrolidin-3-ol (CAS 764715-21-1)
- 1-(((6-Chloropyridin-3-yl)oxy)methyl)-N-methylcyclopropanamine (CAS 712263-55-3)
Recommended Standards
- N-(4-Amino-2-chlorophenyl)isobutyramide (CAS 741271-91-0)
- N-(5-chloropyridin-3-yl)pivalamide (CAS 879326-78-0)
- N-(4-Amino-2-chlorophenyl)butanamide (CAS 723327-05-7)
- N-(6-Chloropyridin-3-yl)pivalamide (CAS 93493-65-3)
- Buramate (CAS 4663-83-6)
- 1-Methyl-4-(sulfinylamino)benzene (CAS 15795-42-3)
- (S)-2-(6-Guanidinohexanamido)-3-(1H-imidazol-4-yl)propanoic acid (CAS 50823-47-7)
- Methyl 2-ethoxy-5-(2-methylthiazol-4-yl)benzoate (CAS 1416344-52-9)
- 4-Bromo-N-(3,4-dimethoxyphenyl)benzamide (CAS 415691-56-4)
- 4-(1-Piperazinyl)-6-(trifluoromethyl)pyrimidine (CAS 845616-55-9)
- N-(2-{[(4-chlorophenyl)carbamoyl]amino}ethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-66-3)
- 4-(4-Methyl-2-pyridyl)benzonitrile (CAS 1187168-55-3)
- Milnacipran Impurity 44 (CAS 105310-28-9)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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