6-((2-Fluorobenzyl)thio)-3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 868968-06-3
| CAS No. | 868968-06-3 |
| Molecular Formula | C17H12FN5S |
| Molecular Weight | 337.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-((2-Fluorobenzyl)thio)-3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-((2-Fluorobenzyl)thio)-3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 868968-06-3) is a high-purity analytical reference standard with the molecular formula C17H12FN5S and a molecular weight of 337.37 g/mol.
The molecular framework of 6-((2-Fluorobenzyl)thio)-3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (C17H12FN5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-((2-Fluorobenzyl)thio)-3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12FN5S |
| Molecular Weight | 337.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- 3-((2-Fluorobenzyl)thio)-6-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 894052-70-1)
- 3-((2-Fluorobenzyl)thio)-6-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 894059-48-4)
- 6-((2-Fluorobenzyl)thio)-3-(pyridin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 868969-21-5)
- 6-((3-Fluorobenzyl)thio)-3-(pyridin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 868969-08-8)
- 5-((4-Fluorobenzyl)amino)-2-((m-tolyloxy)methyl)oxazole-4-carbonitrile (CAS 606948-76-9)
- 2-(2-((4-Fluorobenzyl)thio)-5-(hydroxymethyl)-1H-imidazol-1-yl)-N-isopropylacetamide (CAS 921795-28-0)
- 2-[({4-[(4-Fluorobenzyl)sulfanyl]phenyl}imino)methyl]benzenol (CAS 329779-43-3)
- 6-(3-Fluorobenzyl)-5,7-dimethyl-3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 861206-51-1)
Recommended Standards
- 5-(n-(4-Fluorophenethyl)sulfamoyl)-2-methylbenzoic acid (CAS 794573-83-4)
- 4-Fluoro-N-(6-phenylimidazo[2,1-b]thiazol-5-yl)benzamide (CAS 889768-24-5)
- 4-Ethoxymethylene-2-(4-ethoxy-phenyl)-4H-isoquinoline-1,3-dione (CAS 750607-40-0)
- 6-Hydroxy-4-(morpholinomethyl)-7-phenyl-2H-chromen-2-one (CAS 859142-91-9)
- (3E)-4-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]-1,1,1-trifluoropent-3-en-2-one (CAS 338402-18-9)
- 2-Methoxy-6-methylcyclohex-2-en-1-one (CAS 41577-87-1)
- Methyl DAST (CAS 3880-03-3)
- [S(R)]-N-[(R)-[4-(1,1-Dimethylethyl)phenyl][5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methyl-2-propanesulfinamide (CAS 2160535-58-8)
- Epalrestat Impurity 53 (CAS CATO-C4X-223653)
- rac Mono(3,5,5-trimethylhexyl) Phthalate (CAS 297182-83-3)
- 2',6'-Difluoro-5-methyl-[1,1'-biphenyl]-2-amine (CAS 1341925-26-5)
- 4-(3-Amino-4-chlorophenyl)-2-phenylphthalazin-1(2H)-one (CAS 62335-56-2)
- 7-Octen-1-ol, 3,7-dimethyl-, 1-formate (CAS 141-09-3)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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